NUR 635 Advanced Pharmacology Midterm |Questions and answers with 100% correct solutions | Graded A+

Pharmacology the study of drugs and their structure, targets of action, mechanisms of action (MOA), distribution (how the body disburses them throughout the body), desired physiologic effects (efficacy) and undesirable side effects (toxicity). Pharmacokinetics includes the following: ADME (absorption, distribution, metabolism and elimination). Pharmacokinetics is... How the body effects the drug Absorption absorption from the administration site either directly or indirectly into the blood/plasma. Distribution reversibly/irreversibly movement of drug from the bloodstream into the interstitial and intracellular fluid. Metabolism drug biotransformation via metabolic pathways, primarily the liver, or by other tissues. Elimination how parent drug & its metabolites are eliminated from the body Absorption factors · Gastrointestinal pH changes· Gastric emptying · Gastric/intestinal enzymes · Bile acids & biliary function