Maria Leik All In One Solution.

Product of creatine metabolism, primarily from muscle so falsely decreased in people with low muscle volume (elderly) What raises serum creatinine? -A decrease in renal function such as renal failure or damage, nephrotoxic drugs Which individuals may have higher serum creatinine levels without renal disease? Individuals males and individuals with more muscle mass such as African Americans What is creatinine clearance (24-hr urine) used for? Detect proteinuria, albuminuria and microalbuminuria What is the relative relationship of creatinine clearance (24 hr urine) to GFR? Creatinine clearance is doubled for every 50% reduction in GFR Is 24 hour urine (creatinine clearance) better than serum creatinine? Yes, more sensitive because reflects 24hr period so relatively constant and not affected by fluid status, diet or exercise eGFR definition Amount of fluid filtered by glomerulus within a certain unit of time, used to evaluate renal function Which test is used to stage chronic kidney disease? eGFR, normal 90mL/min, stage 5 (renal failure 15mL/min)