Basic Principles of Clinical Pharmacology Exam Questions with 100% Correct Answers Verified | Updated

Basic Principles of Clinical Pharmacology Exam Questions with 100% Correct Answers Verified | Updated Which of the following statements concerning passage of drugs across membranes is false? a. Small lipophilic drugs can passively diffuse across cell membranes b. The walls of most capillaries do not allow passage of water soluble drugs c. Active transport is able to shuttle proteins against their concentration gradient d. Thiopental easily crosses cell membrane e. The capillaries of the CNS don't allow passive transport of water-soluble drugs - answerB Which of the following statement about drug distribution to the CNS is false? a. Equilibration in the brain and muscle doesn't occur simultaneously b. Diffusion of water-soluble drugs into the brain is severely restricted c. For more polar compounds, the rate of entry into the brain is proportional to their lipid solubility d. Distribution of highly lipid-soluble drugs into the CNS is directly proportional to CBF 3. Recovery from a single dose of thiopental depends primarily on hepatic elimination - answerE Elimination 1/2 life: a. Is not influenced by drug distribution b. Is not influenced by drug elimination c. Is the time it takes the amount of drug in the vessel rich group to decrease by 50% d. Is not influence by age E. Is the time it takes the amount of drug in the body to decrease by 50% - answerE Which statement about drug elimination is false? a. Elimination can occur by excretion of unchanged drug