Unit 4, week 13 UNE biochem Questions & Answers 100% Correct!

False - ANSWERST/F: excess amino acids can be stored Cytosol - ANSWERSProteins with short half-lives or those that are misfolded are degraded in the ____ ATP and ubiquitin - ANSWERSATP mediated protein degradation requires: Ubiquitin - ANSWERSAttachment of ___ changes the conformation of a protein structure targeting it to the proteasome Proteasome - ANSWERSlarge cylindrical protein complex that actively digests protein into AA components Alanine - ANSWERSAA ___ is used for glucose cycle in muscle Alanine and glutamine - ANSWERSthe primary AA in circulation that allow for non toxic transport of ammonia pyridoxal phosphate (PLP) - ANSWERSamino transferases requires the cofactor: glutamate dehydrogenase (GDH) - ANSWERSGlutamate can be deaminated by ____ in a reaction that requires NADH or NADPH Glutamine synthetase - ANSWERSthe enzyme ___ fixes ammonia as glutamine mainly in peripheral tissues for ammonia detoxification Glutaminase - ANSWERSthe enzyme __ deamidates glutamine to glutamate in the liver allowing ammonium to enter the urea cycle Cortisol - ANSWERSprotein catabolism is stimulated by the hormone ____ gluconeogenesis (GNG) - ANSWERSFree amino acids are used as substrate for Glutamate dehydrogenase - ANSWERS____ converts glutamate → α -ketoglutarate (and reverse rxn) and the free ammonium can enter the urea cycle; the resulting alpha ketoglutarate can enter TCA cycle and be used as a substrate for gluconeogenesis Alanine