Chem 1005 Final Exam 2024 Questions & Answers 100% Correct!

In the fasted state, fatty acyl-CoAs are transported across the mitochondrial membrane. The transport of fatty acids via carnitine palmitoyl transferase 1 can be directly inhibited by which of the following compounds? - ANSWERSMalonyl-CoA An individual is on a hunger strike and has not eaten in 13 days. Which of the following best describes their metabolic state? - ANSWERSThe brain will be preferentially oxidizing ketones. Ketonuria, hyperglycemia and severe acidosis are prime diagnostic indicators of the presentation of type 1 diabetes ketoacidosis. Which of the following compounds are ketone bodies that would be elevated in serum and urine of a patient in this condition? - ANSWERSD-3-hydroxybutyrate and acetoacetate In liver, which of the following key inhibitory events ensures that newly synthesized will palmitoyl-CoA is not immediately oxidized? - ANSWERSInhibition of carnitine palmitoyl transferase 1 by malonyl-CoA A 10-year old boy is brought to the emergency department by his father. He reports his son has recently been very thirsty and needing to make frequent trips to the bathroom. Physical examination revealed a thin boy, in the 30th percentile for height and weight. A rapid dipstick test revealed glucose in his urine. Evaluation of this boys blood would reveal decreased levels of which of the following compounds or hormones? - ANSWERSInsulin A 22-year old woman engaging in a political protest goes on a hunger strike on a prominent corner in a city park. She refuses all offers of food except for water through the first 2 weeks. Under these conditions there is a decreased reliance on which of the following pathways for fuel? - ANSWERSGluconeogenesis Which of the following is not a product of B-oxidation? - ANSWERSNADPH ATP can be generated by many metabolic pathways in the body. Which of the following processes generated the most ATP? - ANSWERSFatty acid B-oxidation Which of the following is the regulated step of lipogenesis in eukaryotes? - ANSWERSCarboxylation of acetyl-CoA Under fasting conditions, acetyl CoA carboxylase will be inhibited by an increase in which of the following compounds? - ANSWERSFatty acyl-CoA