Final Exam Review UNE medical biochemistry Exam Questions And Answers

Final Exam Review UNE medical biochemistry Exam Questions And Answers Under fasting conditions (ratio of insulin: glucagon <1), elevated glucagon will activate which of the following enzymes? - ANS hormone sensitive lipase Ketonuria, hypoglycemia, and severe acidosis are prime diagnostic indicators of the presentation of type 1 diabetic ketoacidosis. Which of the following compounds are "ketone bodies" that would be elevated in the serum of urine of a patient in this condition? - ANS D-3-hydroxybutyrate and acetoacetate What is the purpose of cholesterol esterification within the cell? (the conversion of cholesterol to cholesteryl ester) a. this modification makes cholesterol more soluble in the plasma membrane b. this modification does not change the chemical properties of cholesterol c. esterification is the first step in the synthesis of cortisol d. esterification traps cholesterol in the cell - ANS esterification traps cholesterol in the cell An individual goes to bed around 8 pm and doesn't wake up until 9 am the next morning. During this time, which of the following is the primary oxidizable substrate in the skeletal muscle? a. free fatty acids b. glycogen c. amino acids d. lactate - ANS free fatty acids A 22-year-old woman engaging in a political protest goes on a hunger strike on a prominent corner in a city park. She refuses all offers of food for except for water through the first 2 weeks. Under these conditions there is a decreased reliance on which of the following pathways for fuel? a. β-oxidation b. ketogenesis c. gluconeogenesis d. lipolysis - ANS gluconeogenesis In reverse cholesterol transport HDL interacts with the ABCA1 transporter to move cholesterol from the cell to the HDL. This also requires the activity of which of the following enzyme? a. lipoprotein lipase b. cholesteryl ester transfer protein (CETP) c. lecithin cholesterol acyltransferase (LCAT)