CSAM Study Guide Addiction Medicine Exam CSAM

CSAM Study Guide Addiction Medicine Exam CSAM Cyproheptadine - CORRECT ANSWER-5-HT2A receptor antagonist Serotonin syndrome - CORRECT ANSWER-Caused by excessive stimulation of 5-HT2A receptors and possibly 5-HT1A receptors In patients withdrawing from both hypnotic - sedatives and CNS stimulants, which is treated first? - CORRECT ANSWER-hypnotic - sedatives For those patients on both opiates and sedative-hypnotics, which should be tapered first? - CORRECT ANSWER-Taper the sedative-hypnotic first while keeping the opiate dose set at a stable level. Once off the seditive-hypnotic then taper the opiate Codeine is metabolized into morphine by this enzyme: - CORRECT ANSWER-CYP2D6 Methadone is primarily metabolized by this enzyme: - CORRECT ANSWER-CYP3A4 These drugs inhibit CYP 3A4, and thereby slow the elimination of methadone and increase the methadone level: - CORRECT ANSWER-Erythromycin, diltiazem, ketoconazole and sequinavir These drugs induce CYP 3A4, and thereby speed up the elimination of methadone and decrease the methadone level: - CORRECT ANSWER-St. John's wort, carbamzepine, phenobarbital, efavirenz Cocaine induced psychosis versus acute schizophrenia: how do you tell the two apart? - CORRE