ONS/ONCC CHEMOTHERAPY/IMMUNOTHERAPY LESSON 11: TARGETED THERAPIES Exam | Questions & 100% Correct Answers (Verified) | Latest Update | Grade A+

How targeted therapy and chemo differ Correct Answer: -targeted therapies act on specific molecular targets on or within the cells that are associated with cancer, whereas standard chemo act on all rapidly dividing cells-chemo has more SEs-targeted therapy ae chosen and designed to interact with their target on or within the cells, whereas chemo were IDed becaused they kill cells-targeted therapies are often cytostatic (they block tumor cell proliferation) whereas chemo agents are cytotoxic (kill tumor cells) Goals of targeted therapy Correct Answer: -disease cure when used as primary or adjuvant therapy -improving overall response or increase disease-free survival when used in combination with conventional therapies -controlling or stabilizing disease -maintaining or enhancing quality of life 2 -decreasing the severity of toxicities from other therapies Ligand Correct Answer: a substance that forms a complex with another biomolecule to exert a biologic effect Ligand Binding Correct Answer: process by which the ligand attaches to a specific receptor site and activates that receptor, activating the signaling pathway Dimerization Correct Answer: two monomers that are side-by-side on the surface of the cell are paired and activated by a ligand, which causes a series of sign