CHEMOTHERAPY/IMMUNOTHERAPY CERTIFICATE COURSE (ONS,ONCC) Exam | Questions & 100% Correct Answers (Verified) | Latest Update | Grade A+

Alkylating agents Correct Answer: Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) Correct Answer: Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) Correct Answer: Alkylating agent IV CLL or Indolent NHL 2 Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, hepatotoxicity, vein irritation Dose limiting - myelosuppression Irritant and vesicant properties infusion reactions likely to occur in 2nd or subsequent infusions Busulfan (IV busulfex: PO Myleran) Correct Answer: Alkylating Agent IV or PO CML and Stem cell prep Side effects - profound tachycardia, HTN, chest pain, hyperpigmentation, alopecia, infertility, confusion, suizures, mucositis, nausea, vomiting, insomnia, hyperglycemia, blurred vision, secondary malignancy, VOD (now sinusoidal obstruction syndrome) seizure prophylaxis central line only for IV Carboplatin Correct Answer: Alkylating agent IV Ovarian C