ONCC Practice Tests (OCN Treatment Modalities)100% Solved | Already passed
ONCC Practice Tests (OCN Treatment Modalities)100% Solved | Already passed A patient demonstrates an adequate understanding of the teaching provided regarding chemotherapy and myelosuppression by stating: "Myelosuppression is: a potential side effect of many cancer treatments." unintentional prior to a bone marrow transplant." when laboratory values show an elevation in the white blood cell count." the overreaction of the body's immune system to a medication." - a potential side effect of many cancer treatments." Answer: Chemotherapy will decrease the response by the immune system by causing neutropenia, anemia, and thrombocytopenia, collectively known as myelosuppression. Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 171. Alkylating agents exert their effects by: binding to DNA strands, preventing DNA replication and cell division. causing the release of toxic free radicals inside the cell, triggering cell apoptosis. attaching to CD52 on the surface of B and T cells, resulting in antibody-dependent lysis. disrupting folate-dependent metabolic processes essential for cell replication. - binding to DNA strands, preventing DNA replication and cell division. Answer: Alkalyting agents break the DNA helix strand and interfere with DNA replication. Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and biotherapy guidelines and recommendations for practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 27(t).
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