USMLE Step 2 CK With Complete Solution 2024

USMLE Step 2 CK With Complete Solution Argatroban - Direct thrombin inhibitor Contraindicated in Renal Insuficiency Indicated in Liver Disease Fondaparinux - Factor Xa inhibitor Contraindicated in Liver failure Indicated in Kidney Failure Conditions associated to ITP - Lymphoma, leukemia, HIV, HCV, EBV, SLE, alcohol use, chemotherapy lead poisoning - Mild (5-44): no med, repeat levels & relocation Moderate (45-69): DMSA Severe (>70): Dimercaprol + EDTA if encephalopathy Sideroblastic anemia - Basophilic stippling in peripheral smear Ringed sideroblasts only in bone marrow B12 deficiency - MMA and homocysteine Folate deficiency - Normal MMA and increased homocysteine Warm AIHA - SLE, CLL, drugs Cold AIHA - Mycoplasma, mononucleosis, walderstrom macroglobulinemia Polycythemia vera - Hydroxyurea IFN Ruxolitinib (JAK inh.) acute leukemia - >20% blast cells Pleural fluid in TB - Increased protein level (>4g/dL) Increased lymphocytic leukocytosis Decreased glucose levels