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Samenvatting histologie van de orgaanstelsels: Hart, 2e bachelor biomedische wetenschappen

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Samenvatting histologie van de orgaanstelsels: Hart 2e bachelor, 1e semester Biomedische wetenschappen

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Uploaded on
March 18, 2024
Number of pages
2
Written in
2022/2023
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Histologie: Hart

Functies hart en bloedvaten:

 Transport zuurstof en voedingsstoffen
 Transport kooldioxide en afvalstoffen
 Transport hormonen
 Transport immunocompetente cellen en eiwitten
 Transport warmte
 Systeem van bloedstolling
 Pompsysteem

Anatomie en histologie

3 lagen:

 Endocard: endotheel + dunne laag losmazig collageen BW
 Myocard: spierlaag met spoelvormige hartspiercellen
 Epicard: BW met vetcellen, bedekt met mesotheel


Wand linkerventrikel dikker dus grotere
bloedsomloop

Kenmerken hartspierweefsel:

 Spoelvormige hartspiercellen: 1 of 2
kernen/cel, centraal gelegen
 Trapstrepen: mechanische juncties
 Horizontaal: communicatie juncties = gap juncties
 Functionele eenheid = sarcomeer = Z-lijn tot Z-lijn
 Diaden
 Rijk gevasculariseerd
 Veel mitochondriën

Geleidingssysteem

3 onderdelen:

 Nodus sinuatrialis = sinusknoop van Keith-Flack
 Nodus atrioventricularis = atrioventriculaire knoop van Aschoff-Tawara
 Fasciculus atrioventricularis = bundel van His
 Ontspringt in atrioventriculaire knoop
 Splitst in crus dexter en crus sinister -> rafelen uit in vezels van Purkinje

2 typen cellen:

 Nodale cellen
 Gelegen in beide knopen + in begin van bundel
 Zijn gemodifieerde hartcellen, kleiner en rijker aan glycogeen
 Intercalaire schijven en dwarsstreping onduidelijker
 Niet altijd van fibroblasten te onderscheiden
 Weinig georiënteerd netwerk
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