Oxford Cambridge and RSA
Examinations Higher GCSECombined
Science B Twenty First Century
ScienceJ260/01: Biology (Foundation
Tier) General Certificate of Secondary
Education with marking scheme
, Oxford Cambridge and RSA
Tuesday 16 May 2023 – Morning
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/01 Biology (Foundation Tier)
Time allowed: 1 hour 45 minutes
F
* 9 9 3 0 4 1 9 7 5 6 *
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 6 0 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 95.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 32 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2023 [601/8690/2] OCR is an exempt Charity
DC (PQ/SG) 329719/2 Turn over
, 2
1 Some bacteria are pathogens that cause diseases.
(a) Our blood contains white blood cells. They help protect us against pathogens.
(i) Write down the name of the organ that pumps the blood around our body.
...................................................................................................................................... [1]
(ii) Which system are white blood cells a part of?
Tick (3) one box.
Gas exchange system
Immune system
Nervous system
[1]
(b) The human body has different types of defences against pathogens.
Draw lines to connect each type of defence with the correct example.
Type of defence Example
Bacteria in the gut compete
Chemical
against pathogens
Skin stops pathogens
Microbial
entering the body
Stomach acid
Physical
destroys pathogens
[2]
© OCR 2023
, 3
(c) Beth has a cut on her finger.
Platelets in Beth’s blood help to seal the cut so bacteria can’t get into it.
Which two statements explain how her platelets do this?
Tick (3) two boxes.
They carry oxygen.
They make antibodies.
They make her blood clot.
They stick to the edges of the cut.
[2]
© OCR 2023 Turn over
Examinations Higher GCSECombined
Science B Twenty First Century
ScienceJ260/01: Biology (Foundation
Tier) General Certificate of Secondary
Education with marking scheme
, Oxford Cambridge and RSA
Tuesday 16 May 2023 – Morning
GCSE (9–1) Combined Science B
(Twenty First Century Science)
J260/01 Biology (Foundation Tier)
Time allowed: 1 hour 45 minutes
F
* 9 9 3 0 4 1 9 7 5 6 *
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 6 0 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 95.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 32 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2023 [601/8690/2] OCR is an exempt Charity
DC (PQ/SG) 329719/2 Turn over
, 2
1 Some bacteria are pathogens that cause diseases.
(a) Our blood contains white blood cells. They help protect us against pathogens.
(i) Write down the name of the organ that pumps the blood around our body.
...................................................................................................................................... [1]
(ii) Which system are white blood cells a part of?
Tick (3) one box.
Gas exchange system
Immune system
Nervous system
[1]
(b) The human body has different types of defences against pathogens.
Draw lines to connect each type of defence with the correct example.
Type of defence Example
Bacteria in the gut compete
Chemical
against pathogens
Skin stops pathogens
Microbial
entering the body
Stomach acid
Physical
destroys pathogens
[2]
© OCR 2023
, 3
(c) Beth has a cut on her finger.
Platelets in Beth’s blood help to seal the cut so bacteria can’t get into it.
Which two statements explain how her platelets do this?
Tick (3) two boxes.
They carry oxygen.
They make antibodies.
They make her blood clot.
They stick to the edges of the cut.
[2]
© OCR 2023 Turn over