Free Step 2 CK NBME Sec 2-3 question n answers graded A+

Free Step 2 CK NBME Sec 2-3What is the recommended treatment for organophosphate or acetylcholinesterase inhibitor poisoning? - correct answer Atropine (and removal of clothing) Atropine only reverses MUSCARINIC Pralidoxime is the only medication that reverses both muscarinic and nicotinic effects of organophosphates by "restoring" cholinesterase from its bond with these substances. Pralidoxime is effective only if given early after the exposure. ????? - correct answer Cause of heat stroke vs heat exhaustion - correct answer Exertional heat stroke occurs in healthy individuals undergoing conditioning in extreme heat/humidity due to {{c1::thermoregulation failure}} vs heat exhaustion, which is due to inadequate fluid and salt replacement What are potential complications of heat stroke - correct answer Rhabdomyolysis, renal failure, acute respiratory distress syndrome, and disseminated intravascular coagulation (DIC) DIC can lead to coagulopathic bleeding, which explains this patient's persistent epistaxis Heat stroke symptoms - correct answer Acute confusion, hyperthermmia, tachycardia, and persistent epistaxis after exertion under direct sunlight are suggestive of exertional heat stroke - core temp > 40 C (104 F) - CNS dysfunction (AMS) - note that Heat exhaustion does NOT have AMS