CPPS 403 Pre-Midterm Exam Questions with Correct Answers

CPPS 403 Pre-Midterm Exam Questions with Correct Answers Each chromosome contains a single continuous DNA molecule and DNA bound to histone proteins are organized into subunits called nucleosomes. DNA bound around 8 histone proteins. Chromatin - Answer- DNA is condensed into chromatin, condensed into nucleosome. Chromatin fibers are units of DNA wrapped around histones. Chromatin condensed becomes chromatin loops of variable size and there is chromatin domains/topologically association domains (TADs). Chromatin compartments are then segregated into heterochromatin and euchromatin that condense further into chromosomes. Heterochromatin - Answer- Euchromatin - Answer- Chromatin Loop - Answer- The chromatin folding into loops brings upstream gene regulatory elements, like enhancers, into proximity to promoters of genes o control their transcription. Chromatin Domains - Answer- Referred to as TDAs, associate with each other to create chromatin compartments. It is just crumpled up into condensed balls.