PC707 Pharmacology Module 2 Infection Antimicrobials Exam

PC707 Pharmacology Module 2 Infection Antimicrobials Exam ANTIMYCOBACTERIALS & ANTITUBERCULAR Patient Education - Answer ️️ -●Pt adherence crucial d/t long therapy ●Encourage good nutrition, & exercise. ●GI upset common first few weeks of therapy. ●Don't D/C medication if minor adverse effects. ●Take on empty stomach to ↑ absorption. ●Inform if epigastric distress or N occurs can take entire drug protocol w/meals or hour of dosing can be changed. ●Administration with food is preferable to splitting doses or changing to 2nd. line therapy. ●May discolor urine, tears, urine, saliva, & sweat; ●may stain clothing, dentures, & contact lens. ●Rifampin is one agent that DOES interfere with absorption of oral contraceptives, so a CONTRACEPTIVE BACK-UP method is CRUCIAL! Immunizations documentation basics: Document - Answer ️️ -Signed consent form, vaccine, lot, expiration date, VIS given, and location given. Consideration before you immunize - Answer ️️ -• Current Immunization Status of Patient • Immunization Schedule current recommended from CDC • Asses for Contraindications & Precautions • Permission -Vaccine Information Sheet (VIS) Immunizations administration basics: When giving immunizations, - Answer ️️ -make sure they are being given in the right route with the right length of needle (SC,IM). Gestational age at which TDaP is recommended - Answer ️️ -between 27-36 weeks Why is TDaP administration recommended between 27-36 weeks? - Answer ️️ -Allow time for mom to build up immune response to transfer to the baby & have that immune response last until infant can be immunized themselves for pertussis TDap - Answer ️️ -Tetanus Diptheria acellular Pertussis DTaP - Answer ️️ -Diptheria, Tetanus, acellular Pertussis. Formulation used for people 2 months to 6 years old Populations for which pertussis can be lethal - Answer ️️ -newborns and elderly Situations when TDaP can & should be given at other times in pregnancy? - Answer ️️ -Injury with wound, pertussis outbreak, or other circumstance where it would be necessary. Primary reason TDaP is given during pregnancy & why we teach close contacts to also receive - Answer ️️ -to protect baby against Pertussis. Live vaccine - Answer ️️ -Live form, attenuated ; non-infective with low chance of causing disease; leads to long term immunity. (best and longest immune response) more likely to produce side effects Live vaccines contraindications: - Answer ️️ -Do NOT give live vaccines to: 1. pregnant women 2. immunocompormised people 3. Infants < 12 mos of age Killed Vaccine contraindications: - Answer ️️ -Encephalopathy, true allergy (egg > influenza) Reason Infants < 12 months should not get LIVE vaccines - Answer ️️ -they are not mature enough to build a strong immune response. Killed vaccine - Answer ️️ -Contains dead but antigenically active organism; might cause an immune response with symptoms but cannot cause the actual disease. Disadvantage of killed vaccine - Answer ️️ -Provide a shorter duration of protection & needs to be boosted more often. Example of Natural Active Immunity - Answer ️️ -contracting chicken pox & building your own antibodies to the varicell