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Exam (elaborations)

PC 707 Final Safety Exam 2024

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PC 707 Final Safety Exam 2024 IgE mediated allergic reaction that happens after the 2nd exposure to the antigen? - Answer ️️ - Type I Immediate hypersensitivity Delayed Allergic reaction involving T cell in the skin? - Answer ️️ -Type IV Reaction Primary treatment for a Type 1 Allergic response? - Answer ️️ -Epinephrine Adjunctive treatment for a Type 1 Allergic response - Answer ️️ -‣ H1 Blockers ‣ Corticosteroids help prevent bi phasic reactions ‣ Bronchodilators provide some relief- One of the most Severe forms of a Type IV allergic reactions. - Answer ️️ -‣ Stevens Johnson Syndrome ‣ Toxic epidermal necrolysis When considering a drug "re challenge" after reaction what are crucial factors the APRN must consider? - Answer ️️ -‣ What drug the patient reacted to ‣ The severity of the reaction (never again in Type I or severe type IV) *most important* What Black Box Warning does Carbamazepine & Lamictal carry? - Answer ️️ -Potential life- threatening dermatologic reaction, including Steven's Johnson and Toxic Epidermal Necrolysis What Black Box Warning does Promethazine (Phenergan) antiemetic carry? - Answer ️️ -Potential for life threatening respiratory depression in children. What Black Box Warning do Fluoroquinolones carry? - Answer ️️ -Potential for tendon rupture What Black Box Warning does SSRIs carry? - Answer ️️ -Potential increased risk of suicide in teens. What Black Box Warning does opioids carry? - Answer ️️ -Combining opioids & benzodiazepines can cause extreme sleepiness, slowed breathing & death Insulin/Sulfonaureas adverse effect - Answer ️️ -Hypoglycemia! Tricyclic Antidepressants - Answer ️️ -Very risky for overdose Nitrofurantoin (Macrobid) adverse effect - Answer ️️ -Pulmonary Toxicity (rare )

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