PC707 PHARMACOLOGY FINAL- SAFETY EXAM QUESTIONS WITH CORRECT ANSWERS

PC707 PHARMACOLOGY FINAL- SAFETY EXAM QUESTIONS WITH CORRECT ANSWERS Does the pdr provide up to date info on pregnancy and lactation? - answer ️️ -no, It is a compilation of package inserts, without much updating Best resources for drugs in pregnancy and lactation - answer ️️ -lactmed and otis (organization of tetraology information specialists) Do medical foods need to be administered under the direction of a provider? - answer ️️ -yes What are risk factors for drug resistant pathogens - answer ️️ -recent antibiotic use, younger than 2, older than 65, daycare attendance (not college), exposure to young children, comorbidities, recent hospitalizations, immunosuppression. What are the safest remedies/drugs to use for constipation in pregnancy? - answer ️️ -bulk forming laxatives and glycerin suppositories Metformin is contraindicated in those with kidney disease, at what creatinine levels should metformin not be given - answer ️️ -serum creatinine greater than 1.5 in men and 1.4 in women Drug half life - answer ️️ -the time it takes for the drug concentration to decrease by half in the serum Metabolism - answer ️️ -the chemical alteration of drugs by the body's enzymes Type 1 reaction - answer ️️ -ige- mediated. Immediate hypersensitivty reaction, atopic reaction, hives, anaphlaxysis, angioedema Type 2 reaction - answer ️️ -antibody dependent cytotoxicity (i.e. heparin induced thrombocytopenia) Type 3 reaction - answer ️️ -immune complex hypersensitivity (arthus reaction to tetanus vaccine) Type 4 reaction - answer ️️ -cell mediated delayed hypersenstivity: drug rash, eosinophilia and systemic syndrome.