PC707-Module 10 Exam Study Guide with Complete Solutions

PC707-Module 10 Exam Study Guide with Complete Solutions PC707-Module 10 Exam Study Guide with Complete Solutions PC707-Module 10 Exam Study Guide with Complete Solutions Diabetes Medication - Sulfonylureas - ANSWER--Action = Stimulates pancreatic insulin release. -Adverse effects = Hypoglycemia, Weight gain, Increased risk of CV mortality. -Contraindications = Impaired renal function. *Are not contraindicated in pts. with sulfa allergy due to different molecular structure (Let's talk & camtasia/text says to not use with sulfa allergy).* Diabetes Medication - Biguanides - ANSWER-(1st line therapy) -Action = Enhances receptor sensitivity to insulin in muscle and fat. -Adverse effects = Causes nausea, cramps, and diarrhea *take with meals* -Contraindications = CHF, Renal impairment, Liver disease, >80 years of age, Severe infection, COPD, Excessive alcohol consumption. May cause megaloblastic anemia over time. *Cannot cause hypoglycemia thus are safer for patients at risk.* Diabetes Medication - Gliptins - ANSWER--Action = Inhibits degradation of endogenous incretins which increase insulin secretion, decreases glucagon secretion & decreases hepatic glucose production.