NAPSR Exam Quiz 10, exam questions
with complete answers
(T/F) The aim of preclinical pharmacological studies is to obtain data on the safety and
effectiveness of the lead compound. - Answer-True
(T/F) Toxicity information in preclinical studies helps provide confidence about a drug's
safety. - Answer-True
(T/F)Pharmacological studies using animals are regulated under Good Laboratory
Practice. - Answer-True
Why do drugs administered to patients only contain APIs? - Answer-They don't
Which of the following does NOT affect a drug's ability to permeate membranes? -
Answer-the drugs vesicles
Through which barriers can lipid-soluble drugs usually pass? - Answer-cell membranes
How are weak acid drugs generally absorbed by the stomach? - Answer-more quickly
than weak basic drugs
Which of the following routes of administration do NOT completely bypass the liver? -
Answer-rectal administration
Why are intravenous drug dosages easier to control than drugs administered
transdermally? - Answer-the entire dose is available in the bloodstream to be distributed
to the target site
Which of the following does NOT affect a drug's distribution to its target tissues? -
Answer-all of these factors affect a drug's distribution to its target tissues
(1. the drug's lipid-solubility
2. the drugs polarity
3. the vascular nature of the drug's target tissue)
Which of these medical terms means "to apply the drug on the skin surface"? - Answer-
Transdermal
(T/F) Carcinogenicity studies are carried out to identify the tumor-causing potential of a
drug. - Answer-true
Which of the below is the least commonly analyzed fluid for conducting a medical
diagnostic test? - Answer-Salive
with complete answers
(T/F) The aim of preclinical pharmacological studies is to obtain data on the safety and
effectiveness of the lead compound. - Answer-True
(T/F) Toxicity information in preclinical studies helps provide confidence about a drug's
safety. - Answer-True
(T/F)Pharmacological studies using animals are regulated under Good Laboratory
Practice. - Answer-True
Why do drugs administered to patients only contain APIs? - Answer-They don't
Which of the following does NOT affect a drug's ability to permeate membranes? -
Answer-the drugs vesicles
Through which barriers can lipid-soluble drugs usually pass? - Answer-cell membranes
How are weak acid drugs generally absorbed by the stomach? - Answer-more quickly
than weak basic drugs
Which of the following routes of administration do NOT completely bypass the liver? -
Answer-rectal administration
Why are intravenous drug dosages easier to control than drugs administered
transdermally? - Answer-the entire dose is available in the bloodstream to be distributed
to the target site
Which of the following does NOT affect a drug's distribution to its target tissues? -
Answer-all of these factors affect a drug's distribution to its target tissues
(1. the drug's lipid-solubility
2. the drugs polarity
3. the vascular nature of the drug's target tissue)
Which of these medical terms means "to apply the drug on the skin surface"? - Answer-
Transdermal
(T/F) Carcinogenicity studies are carried out to identify the tumor-causing potential of a
drug. - Answer-true
Which of the below is the least commonly analyzed fluid for conducting a medical
diagnostic test? - Answer-Salive
