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College Nierinsufficiëntie samenvatting leerjaar 1

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College nierinsufficiëntie samenvatting blok 1 jaar 1

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February 6, 2018
Number of pages
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Written in
2017/2018
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College Nierinsufficiëntie

 Plotselinge en ernstige vermindering in de glomerulaire filtratie  acute nierinsufficiëntie
- Oligurie (<500 ml urine productie per 24h)
- Anurie (<50 ml urine productie per 24h)
- Metabolische acidose
- Opeenstapeling van afvalstoffen in het lichaam (ureum en urinezuur)



 Prerenaal – verminderde bloedstroom in de nier
 Renaal – schade aan de nieren
 Postrenaal – obstructie in de nieren (tumoren, nierstenen)



Chronische nierinsufficiëntie

 75 % van de nefronen is beshadigd
 Onomkeerbaar proces
 Diabetes, glomerulonephritis en hypertensie
 Polyurie (grote hoeveelheid urine)
 Acidose
 Verstoorde hoeveelheden urine)
 Anemie
- Tekort aan EPO
- Vermindere productie rode boedcellen
 Hypertensie



Nefrotisch syndroom

 Gevolg van nieraandoeningen
- Verlies van albumine via de urine (proteïnurie)
- Tekort aan albumine in het bloed
- Albumine voorkomt het weglekken van water uit de bloedvaten
- Tekort aan albumine  verlies aan water uit de bloedvaten en vochtophoping in de
weefsels  oedeemvorming
- Hyperlipidemie  verhoogde vetophoping
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