NURS 6501 Endocrine

NURS 6501 Endocrine
Autocrine
Control in a cell
Paracrine
Control / communication between local cells
Endocrine
control/ communication between cells that are far from each other
Hormone secretion pattern
a) Diurnal b) pulsatile and cyclic c) Patterns that depend on levels of circulating
substrates
ELISA
Enzyme-Linked Immunosorbent Assay: used to determine circulating hormone levels.
a technique used to detect antibodies or infectious agents in a sample. Antibodies
are made in response to infection and so an antibody ELISA can indicate whether or not
an animal has been in contact with a certain virus.
Thyrotropin-releasing hormone (TRH)
Anterior pituitary
Stimulates release of thyroid-stimulating hormone (TSH): modulates prolactin secretion
Gonadotropin-releasing hormone (GnRH)
Anterior Pituitary
Simulates release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
Somatostatin
Anterior Pituitary
Inhibits release of growth hormone (GH) and TSH
Growth hormone-releasing hormone (GHRH)
Anterior Pituitary
Stimulates release of GH
Corticotropin-releasing hormone (CRH)
Anterior Pituitary
Stimulates the release of adrenocorticotropic hormone (ACTH) and Beta-Endorphin
Substance P
Anterior Pituitary
Inhibits synthesis and release of ACTH; Stimulates secretion of GH, FSH, LH, and
prolactin
Prolactin-hinhibiting factor (PIF, dopamine)
Anterior Pituitary
Inhibits synthesis and secretion of prolactin
Prolactin-releasing factor (PFR)
Anterior Pituitary
Stimulates secretion of prolactin
Somatopause
a gradual and progressive decrease in growth hormone secretion that occurs normally
with increasing age during adult life and is associated with an increase in adipose tissue
and LDL levels and a decrease in lean body mass
SIADH