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samenvatting behandelingen dermatologie

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Dit is een samenvatting van alle ziekten die we gezien hebben tijdens de lessen van dermatologie en de behandelingsprincipes. Ik vond dit een zeer handig document om de dag voor het examen / de ochtend van het examen nog te bekijken. Ook komen er in het examen veel vragen over behandelingen terug. Misschien heeft dit documentje me geholpen om een 19/20 te halen... ;)

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December 2, 2023
Number of pages
11
Written in
2022/2023
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Summary

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BEHANDELINGEN DERMATO

Eczeem
Atopisch eczeem
Algemene maatregelen (onderhoudstherapie altijd!)
- Uitleg
- Hydratatie
o Wasinstructies
o Emollientia (hydraterende crèmes)
 2x/d
 100g -> 250g/w
- Vermijden uitlokkende factoren
- Psychische ondersteuning

Actieve therapie
1. Lokaal:
a. Corticosteroiden
i. 1-2w dagelijks -> 1-2w/d -> 2x/w
b. Calcineurine inhibitoren
i. Geen huidatrofie
ii. Mag langdurig!
iii. AE: soms branderig
2. UV therapie
3. Systemische immuunsupressie
a. Cyclosporine -> nierschade!
b. Azathioprine
c. Methotrexaat
4. Biologicals
a. Dupilumab
b. Barcitinib

Behandeling surinfectie
bacterieel = geïmpetiginiseerd
- Lokale antiseptica
- Lokale AB: fusidinezuur
- Orale AB: flucloxacilline
Viraal = eczema herpeticum
- (val)aciclovir

Behandeling jeuk
1. Goede hydratatie + anti-inflammatoir
2. H1 anti-histaminica

, Seborreisch eczeem
1. Anti-malassezia (+/- ontschilferend)
a. Aanval: 2w
b. Onderhoud: 1-2x/w
2. Meer inflammatie?
a. Lokale corticosteroïden
b. 1w -> 1w om de dag -> STOP
Vehiculum?
- Scalp -> shampoo / lotion
- Gelaat + lichaam -> crème

3. Uitgebreide/ therapieresistente vormen
a. Systemisch anti-malassezia: itraconazole
i. Aanval: 2x100mg/d 1w
ii. Onderhoud: 2x2x100mg d1 -> d15 `




Psoriasis
Milde tot matige gelokaliseerde
- Lokale corticosteroiden
- In monotherapie of combi vitD
Matige tot ernstige, niet reagerend op lokale therapie
- Small spectrum UVB
- PUVA
Ernstige psoriasis, lokale therapie onvoldoende
- Acitretine
o pustulaire vorm als monotherapie
o anders: combi (Cs of foto(chemo)R/)
- MTX -> pso-artritis
- Cyclosporine -> potentieel nefrotoxisch
- Biologics
o TNF-alfa
o Interleukine (12/23)
o IL-17

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