MN 553 Advanced Pharmacology Final Exam Latest Update (ACTUAL EXAM)

Jim is being treated for hypertension. Because he has a history of heart attack, the drug chosen is atenolol. Beta blockers treat hypertension by: Question options: Increasing heart rate to improve cardiac output Reducing vascular smooth muscle tone Increasing aldosterone-mediated volume activity Reducing aqueous humor production Opiates are used mainly to treat moderate to severe pain. Which of the following is NOT true about these drugs? Question options: All opiates are scheduled drugs which require a DEA license to prescribe. Opiates stimulate only mu receptors for the control of pain. Most of the adverse effects of opiates are related to mu receptor stimulation. Naloxone is an antagonist to opiates. When considering which cholesterol-lowering drug to prescribe, which factor determines the type and intensity of treatment? Question options: Total LDL Fasting HDL Coronary artery disease risk level Fasting total cholesterol Being competent in the use of information technology in clinical practice is expected in professional nurses. Advanced practice competence includes the ability to: Question options: Search for information using the most common search engines Serve as content experts in developing, implementing, and evaluating information Systems Write programs to assure the integrity of health information Use information technology to prescribe drugs The New York Heart Association and the Canadian Cardiovascular Society have described grading criteria for levels of angina. Angina that occurs with unusually strenuous activity or on walking or climbing stair after meals is class: Question options: I II III IV An Investigational New Drug is filed with the U.S. Food and Drug Administration: Question options: When the manufacturer has completed phase III trials When a new drug is discovered Prior to animal testing of any new drug entity Prior to human testing of any new drug entity True contraindications to diphtheria, tetanus, and acellular pertussis (DTaP or Tdap) vaccine include: Question options: Fever up to 104oF (40.5oC) after previous DTaP vaccine Family history of seizures after DTaP vaccine Adolescent pregnancy Anaphylactic reaction with a previous dose A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to: Question options: Ensure the patient will not have increased adverse drug reactions to the tamoxifen Identify potential drug-drug interactions that may occur with tamoxifen Reduce the likelihood of therapeutic failure with tamoxifen treatment Identify poor metabolizers of tamoxifen Several classes of drugs have interactions with cholinergic blockers. Which of the following is true about these interactions? Question options: Drugs with a narrow therapeutic range given orally may not stay in the GI tract long enough to prodAdditive antimuscarinic effects may occur with antihistamines. Cholinergic blockers may decrease the sedative effects of hypnotics. Cholinergic blockers are contraindicated with antipsychotics. Absolute contraindications that clinicians must consider when initiating estrogen therapy include: Question options: Undiagnosed dysfunctional uterine bleeding Deep vein or arterial thromboemboli within the prior year Endometriosis Both a. and b. All of the above