Pharmacology HESI V2 Preparation 2023/2024

Pharmacology HESI V2 Preparation 2023/2024 A client is prescribed phenobarbital sodium (Luminal) for a seizure disorder. The medication has a long half-life of 4 days. Based on this half-life, the medication will most likely be prescribed A. once a day. B. twice a day. C. three times a day. D. four times a day. - ANSWER ANS: A Medication with long half-lives remain at their therapeutic levels between doses for long periods of time. Therefore, this medication can be administered once a day. A nurse educator is reviewing medication dosages and factors that influence medication metabolism with a group of nurses. Medication dosages may need to be decreased for which of the following reasons? (Select all that apply.) A. Increased renal excretion B. Increased medication-metabolizing enzymes C. Liver failure D. Peripheral vascular disease E. Concurrent use of medication metabolized by the same pathway - ANSWER ANS: C, E Liver failure decreases metabolism and thus increase the concentration of medication. This may require decreasing the dosage of medication. When two medications are metabolized in the same way, they may compete for metabolism, thereby increasing the concentration of one or both medications. Increased renal excretion may decrease concentration of the medication, requiring increased dosage. Increased medication-metabolizing enzymes can decrease the concentration of the medication. The dose might need increased. Peripheral vascular disease may impair distribution, and more of the medication may be needed. A nurse s preparing to administer eye drops to a client. Which of the following are appropriate nursing interventions related to this procedure? (Select all that apply.) A. Using medical aseptic technique B. Asking the client to look up at the ceiling C. Having the client lie in a side-lying position D. Dropping medication into the center of the client's conjunctival sac E. Instructing the client to close the eye gently - ANSWER ANS:B, D, E The medication should be dropped into the center of the conjunctival sac to promote better distribution of the medication. The client should close the eye gently to allow improved distribution of the medication. Surgical aseptic technique is used to administer eye drops. The client should be sitting or in a supine position to facilitate proper administration of eye drops. A nurse is completing discharge teaching to a client who has a new prescription for a transdermal medication. Which of the following statements by the client indicates understanding of the teaching? A. "I will clean the site with an alcohol swab prior to applying the patch." B. "I will rotate the application site weekly." C. "I will apply the patch to an area of skin with no hair." D. "I will place the new patch on the site of the old patch." - ANSWER ANS: C Transdermal medication should be applied to a hairless area of skin to promote absorption of medication. The skin should be washed with soap and water and dried thoroughly before applying a transdermal patch. Application sites should be rotated on a daily basis to prevent skin irritation. A nurse is reviewing a client's health record and notes a new prescription by the provider to verify the trough level of the client's medication. Which of the following actions should the nurse take? A. Have a blood specimen obtained immediately prior to the next dose of medication. B. Verify that the client has been on the medication for 24 hr before ordering a blood specimen. C. Ask the client to provide a urine specimen after the next dose of medication. D. Begin administering the medication, and obtain a blood specimen. - ANSWER ANS: A To verify trough levels of a medication, a blood specimen is obtained immediately before the next dose of medication. A nurse is preparing a client's medication. Which of the following are legal responsibilities of the nurse? (Select all that apply.) A. Maintaining skill competency B. Determining the dosage C. Monitoring for adverse effects D. Safeguarding medications E. Identifying the client's diagnosis - ANSWER ANS: A, C, D Determining medication dosage and identifying a diagnosis is the role/responsibility of the provider. The nurse should be informed about a client's diagnosis.