BMTCN Exam Practice Questions well answered graded A+

BMTCN Exam Practice QuestionsWhen a patient senses a leaking in IV site during a chemotherapy infusion, what does the nurse do first? A. Place warning signs across the area to alert others to the spill B. Restart the chemotherapy with a new order C. Put on the right safety gear D. Environmental programs should be contacted - correct answer A. Place a warning signs across the area to alert others to the spill Explanation: People who treat or come into contact with chemotherapy drugs are known to be at risk. This suggests that the medicines are powerful enough to harm or destroy cancer cells, which is good news for patients. However, this means that drugs could pose a risk to those who are exposed to them. This is why chemo drug handlers must adhere to such safety guidelines and recommendations. If IV chemo is spilled, powder or dust from a pill or tablet, or liquid from oral or other types of chemo is present, it may be dangerous to others. Which of the following is the leading cause of death after a cord blood transplant? A. Infection B. Bleeding C. Malnutrition D. Renal Failure - correct answer A. Infection Explanation: Like bone marrow and peripheral blood, umbilical cord blood is risk source of stem cells for transplantation. It does, however, come with a few risks. "Infection" is one of the most serious risks that can lead to death. Infection is thought to be responsible for 35-50% of non-relapse mortality in UCBT patients, compared to 8-22% in allogeneic HCT patients. Following UCBT, viral infection, particularly cytomegalovirus (CMV) and human herpesvirus 6 (HHV-6), have been linked to an increase in morbidity and death. Which of the following drugs will most likely lead to heart failure as being used in the conditioning regimen? A. Busulfan B. Cytarabine C. Fludarabine D. Cyclophosphamide - correct answer D. Cyclophosphamide Explanation: Cardiac toxicity is the result of harmful chemicals causing damage to the heart. Toxins (drugs) may be administered to you as part of your treatment to destroy cancer cells. Normal cells in and around your heart can also be killed as a side effect. Patients taking a cumulative dose of more than 150mg/kg cyclophosphamide have a 7-33% chance of developing acute heart failure. Depending on the dosing regimen and patient population, fatal cyclophosphamide cardiomyopathy can range from 2 to 17%. Daisy has leukemia. She will require HSCT treatment. In this situation, which of the following is the most important thing for the nurse to consider while teaching her caregiver? A. Request that the teaching be done by a nurse who is not caring for the patient B. Discuss the probability of transferring the details to someone other than the caregiver C. Concentrate on details about the present stage of treatment D. Keep track of the caregiver's emotional reaction - correct answer C. Concentrate on details about the present stage of treatment Explanation: A successful caregiver must have the ability to develop adequate coping strategies, solve problems, and prioritize. To be able to offer adequate treatment for an HSCT recipient, the caregiver must preserve his or her own quality of life -- including mental, physical, and emotional health -- during the transplanting phase. Since the conditions of patients and their caregivers change with each phase of treatment, it's critical to customize teaching to the particular phase of treatment. Under utilization for certain diseases occurs due to transplant-related toxicity. For which of the following disease is transplant-related toxicity a barrier? A. Neuroblastoma B. Arrhythmia C. Acute Myeloid Leukemia D. Sickle Cell Disease - correct answer D. Sickle Cell Disease Explanation: While the clinical course of sickle cell disease (SCD) varies, many patients experience end-organ complications that are associated with severe morbidity and mortality. While myeloablative allogeneic HSCT (allo-HSCT) is curative, it has traditionally been reserved for children under the age of 16. Sickle cell disease (SCD) is triggered by a single nucleotide mutation in the -globin protein, which replaces glutamate with valine in the 6th spot. The hemoglobin protein is more likely to polymerize when deoxygenated as a result of this transition, resulting in sickle-shaped red cells.