BMTCN Numbers to Know question n answers graded A+

BMTCN Numbers to KnowLeukapheresis - Peripheral blood stem cell collection: goal # cells in adults vs. pediatrics, how much blood commonly processed - Bone marrow: goal # cells, how much marrow obtained - correct answer PBSCs: 5 x10^6 CD34+ cells per kg of recipient's body weight - Adults: 12-15L of blood commonly processed - Pediatrics: 200-250 mL/kg of blood commonly processed **If < 25kg, will require a blood prime to offset anemia Bone marrow: 2-3 x 10^8 nucleated cells per kg of recipient's body weight - 1-2 L marrow volume usually obtained Harvest volumes - correct answer Based on size of recipient and donor - Harvest 10-15 mL/kg the patient's weight - Maximum harvest volume is 15-20 mL/kg the donor Harvest range Total Nucleated Cell count (TNC) - correct answer 1-4 x 10^8 mL/kg of recipient weight