PSYCH 643 REGIS PRIOR EXAM WEEK 3 QUESTIONS WITH ANSWERS UPDATE

PSYCH 643 REGIS PRIOR EXAM WEEK 3 QUESTIONS WITH ANSWERS UPDATE Week 3 Quiz 1. Volume neurotransmission refers to? The diffusion of neurotransmitter to nearby neurons. 2. Retrograde neurotransmissions refers to? The flow of neurotransmitter from postsynaptic neuron to presynaptic neuron 3. Use the following CYP450 table to hypothesize drug interactions and their clinical significance for a patient on clozapine who carbamazepine, a mood stabilizer? Clozapine levels would decrease, placing the patient at risk for re-emergence of psychotic symptoms. 4. In ligand-gated ion channels, an? Antagonist, in the presence of an agonist, can return a channel to resting state. 5. Which of the following statements about drug absorption is trued? Concurrent use of some medications can slow absorption. 6. A neurotransmitter binds to a receptor, causing electrical impulses to travel the neuron’s axon; it eventually releases the neurotransmitter and repeats the process with a postsynaptic neuron. Which type of neurotransmission does this describe? Classic synaptic neurotransmission 7. Which of the following statements is true about drug distribution? Protein binding of psychotropic drugs can impact their availability at receptor sites. 8. Which of the following statements is true about neuronal gene expression? Environmental factors can alter a neuron’s gene expression. 9. First pass effect refers to the? Metabolism of the drug in the liver, prior to reaching systemic circulation 10. Matching the following. Pharmacodynamics- Action of drugs on the body Pharmacokinetics- Action of the body on the drugs Axon- The fiber-like part of the neuron that sends information to receiving neurons Ionic filter- Regulates the flow of ions in ligand-gated channels Excitation-secretion coupling- The conversion of an electrical signal to a chemical signal Dendrite- The point of contact for receiving information from neurons in the classical neurotransmission 11. Use the following CYP450 table to hypothesize drug interactions and their clinical significance for a patient on haloperidol, a conventional antipsychotic, who is prescribed paroxetine, an antidepressant? Haloperidol levels would increase, placing the patient at risk for antipsychotic side effects. 12. Elimination of a drug can be impacted by all of the following scenarios except? A Mediterranean diet. 13. Which of the following statements is true about ligand-gated ion channels? Allosteric modulators can enhance or inhibit ion channels when in the presence of neurotransmitter. 14. Pharmacokinetics involves consideration all of the following except the?