663 Exam 1 Study Guide GRADE A+

663 Exam 1 Study Guide GRADE A+ Bipolar Disorder Type 1 - CORRECT ANSWER-- MDD (2 weeks) - Mania (1 week) - plus 3 or more: inflated self esteem, decreased need for sleep, talkative, flight of ideas, distractability, goal directed, excessive involvement - severe - marked impairment Mnemonic for Bipolar Disorder - CORRECT ANSWER-DIGFAST Bipolar Disorder Type 2 - CORRECT ANSWER-- MDD (2weeks) - current or past episode of hypomania (4 days) - not severe enough to cause marked impairment Cyclothymia - CORRECT ANSWER-- 2 years - numerous periods of hypomanic sx - chronic, fluctuating mood disturbance - sx free no longer than 2 months Dysthymia - CORRECT ANSWER-- depressed mood for 2 years - 2 or more: poor appetite, overeating, insomnia, hypersomnia, low energy, fatigue, low self esteem, poor concentration, feeling hopeless - "down in the dumps" Hypomania - CORRECT ANSWER-- elevated, expansive, irritable mood - persistently increased activity or energy - lasts only 4 days - not severe Major Depressive Disorder - CORRECT ANSWER-- 5 or more during 2 week period: depressed mood, loss of interest, weight loss/gain, insomnia/hypersomnia, psychomotor agitation/retardation, fatigue, worthlessness/guilt, diminished ability to think, recurrent thoughts of death Modifiable Risks for Suicide - CORRECT ANSWER-- abuse - unrealistic parental expectations - extreme perfectionism - mental illness - substance abuse - poor coping/social skills - impulsivity - chronic severe stress - ongoing harassment Nonmodifiable Risk Factors for Suicide - CORRECT ANSWER-- family hx of suicide - family hx of mental illness - family hx of substance abuse - race - gender - previous attempt - loss through death, abandonment or divorce - inconsistent, neglectful or abusive parenting - sexual orientation - gender identity - experience of repeated loss Who qualifies for involuntary commitment - CORRECT ANSWER-- danger to self - danger to others - gravely disabled due to mental illness Criteria for involuntary commitment - CORRECT ANSWER-- individual has a mental illness, developmental disability or drug/alcohol dependence - individuals illness/disability/dependence is treatable - dangerous to themselves or others Mental illness criteria for involuntary commitment - CORRECT ANSWER-- substantial disorder of thought, mood, preception, orientation or memory - grossly impaired judgement, behavior, capacity to recognize reality or ability to meet demands of life Developmental disability criteria for involuntary commitment - CORRECT ANSWER-- brain injury - autism - Prader Willi Syndrome - IDD - expected to continue indefinitely - substantial handicap to the individual Drug dependence criteria for involuntary commitment - CORRECT ANSWER-- dependency to one or more drugs - health is substantially impaired - social or economic functioning is substantially impaired Alcoholism criteria for involuntary commitment - CORRECT ANSWER-- dependency on alcohol - health is substantially impaired or endangered - social or economic functioning is substantially disrupted Pt rights during involuntary commitment - CORRECT ANSWER-- refuse meds - free of restraints - engage in religious worship - confidentiality Medical conditions that mimic mania (intoxication or use) - CORRECT ANSWER-- alcohol intoxication - LSD - meth - benzo - steroids - isoniazid - thyroxine - zidovudine Medical conditions that mimic mania (withdrawal) - CORRECT ANSWER-- alcohol - benzos - beta blockers Medical conditions that mimic mania (Metabolic) - CORRECT ANSWER-- hemodialysis - post op - thyrotoxicosis - B 12 deficiency - cushings Medical conditions that mimic mania (infectious) - CORRECT ANSWER-- flu - encephalitis - HIV - neurosyphilis Medical conditions that mimic mania (neurologic) - CORRECT ANSWER-- neoplasm - complex partial seizure - Wilsons disease - Huntington's - MS - stroke Medical conditions that mimic depression (intoxication or use) - CORRECT ANSWER-- opiates - benzos - anticonvulsants - alcohol - reserpine Medical conditions that mimic depression (withdrawal) - CORRECT ANSWER-- cocaine - meth Medical conditions that mimic depression (metabolic) - CORRECT ANSWER-- uremia - niacin deficiency - B 12 deficiency - anemia - hypothyroidism - Cushings - Addisons - Sleep apnea - heavy metal toxicity - paraneoplastic syndrome Medical conditions that mimic depression (infectious) - CORRECT ANSWER-- lyme disease - neurosyphilis - HIV - bechets - meningitis Medical conditions that mimic depression (Neuro) - CORRECT ANSWER-- ischemia - stroke - neoplasm - complex partial seizure - postictal state - normal pressure hydrocephalus - parkinsons What class is Bupropion - CORRECT ANSWER-- dopamine reuptake inhibitor and releaser - norepinephrine dopamine reuptake inhibitor - antidepressant - smoking cessation Bupropion FDA - CORRECT ANSWER-- MDD - SAD - nicotine addiction How does Bupropion work - CORRECT ANSWER-- boost noreinephrnine/noradrenaline and dopamine - blocks norepinenphrine reuptake pump - increase dopamine neurotransmission - block dopamine reuptake pump Side effects of Bupropion - CORRECT ANSWER-- dry mouth - constipation - nausea - weight loss - anorexia - myalgia - insomnia - dizziness - headache - agitation - anxiety - tremor - abd pain - tinnitus - sweating - rash - HTN Life threatening side effects of Bupropion - CORRECT ANSWER-- seizures - stevens johnsons - hypomania - mania Do not give buporpion to - CORRECT ANSWER-- TBI - seizure disorder Bupropion pharmacokinetics - CORRECT ANSWER-- inhibits cyp450 2D6 - half life of 10-14 hours - food does not affect absorption Bupropion drug interactions - CORRECT ANSWER-- increase TCA levels - wait 14 days with MAOI What class is Carbamazepine - CORRECT ANSWER-- glutamate, voltage gated sodium and calcium channel blocker - anticonvulsant FDA Carbamazepine - CORRECT ANSWER-- seizures - acute mania - mixed mania How does Carbamazepine work? - CORRECT ANSWER-- blocker of voltage sensitive sodium channels - inhibits release of glutamate