WGU D027 pathopharm Questions and Answers 100% Correct(SCORED A+)

Mechanism of Action for loop diuretics - ANSWER-block water reasborption in the loop of Henle of nephron. Increases urine output Suffix for loop - ANSWER--emide ex: furosemide cautions in using loop diuretics - ANSWER-decreased potassium, decreased BP, ototoxicity, nephrotoxicity USE WITH CAUTION in those who have auditory/renal impairments Suffix for Thiazide Diuretics - ANSWER--thiazide MOA for thiazide diuretics - ANSWER-blood water reabsorption in distal tube of nephron-- increases urine output adverse drug reactions for thiazide diuretics - ANSWER-decreases potassium, increases uric acid, increases calcium AVOID use in hx with gout, use cautiously with kidney disease Contraindicator for thiazide diuretics - ANSWER-those with sulfa allergies, contains sulfa group in molecular structure. Also avoid in hx of gout due to increase of uric acid Aldosterone antagonists MOA - ANSWER-inhibits aldosterone which results in sodium loss in the nephron, water follows and is excreted, potassium is retained (potassium sparing diuretic) example of an aldosterone antagonist - ANSWER-Spironolactone adverse drug reactions for aldosterone antagonists - ANSWER-high potassium, androgen blocking (blocks testosterone and causes estrogen effects) beta blocker examples - ANSWER-Propranolol (Inderal) Metroprolol (Lopressor/Toprol XL) Atenolol (Tenormin) Carvedilol (Coreg) MOA of beta blockers - ANSWER-block adrenergic effects of Beta 1 and Beta 2 rec