ACTIVE LEARNING TEMPLATE: Medication
STUDENT NAME _____________________________________
Methotrexate
MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________
DMARDS
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
Slow joint degeneration and progression of Analgesia for pain, swelling, and joint
rheumatoid arthritis stiffness, maintain of joint function,
management of inflammatory bowel disease
Complications Medication Administration
Increased risk for infection(notified for sore throat, fever),
hepatic fibrosis and toxicity (notify if anorexia, abdominal
fullness, jaundice occur), bone marrow suppression,
ulcerative stomatitis TOXICITY (ulcerations, bleeding, colo
Contraindications/Precautions
Preach, lactation, teratogenic, liver failure, alcohol use
disorder, blood dycrasias. Cautiously in liver or kidney
dysfunction, peptic ulcer disease, ulcerative colitis, cancer Nursing Interventions
or bone marrow suppression, impaired nutritional status,
infections, and children
Interactions
Salicylate, NSAIDs, sulfonamides, penicillin, and other
tetracyclines can cause toxicity (ulcerative stomatitis.
Inspect mouth gums and throat for color changes,
bleeding, and ulceration. Use soft toothbrush, and stop
medication. folic acid= reduce effectiveness Client Education
Effects are delayed and can
take 3-6 weeks to take full effect
Evaluation of Medication Effectiveness
ACTIVE LEARNING TEMPLATES THERAPEUTIC PROCEDURE A7
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