ISBB REVIEW QUESTIONS and answers graded A+ 2023 passed

ISBB REVIEW QUESTIONSY. entercolitica Most common contaminant in blood bags Rubeola 2 weeks Rubella 4 weeks platelet concentrate 5.5 x 10 to the 11th power (whole blood) platelet concentrate 3.0 x 10 to the 11th power (apheresis) Cryoprecipitate Heavy spin 56C for 30 min. Inactivation of serum 56C for 10 min Reinactivation of serum 10 minutes How many minutes does HBV inactivates using 1:100 dilution S. epidermidis B. cereus (StarBucks) Room Temp Blood Bag contaminants P.flourescens S.liquifaciens Y.entercolitica (Pangako Sa'Yo) 4 C blood bag contaminants Variolation/ Insufflation Chinese Inhalation of pulverized crust of smallpox lesions Edward Jenner demonstarted cross-immunity Vaccinia causes COWPOX Variola major cause of SMALLPOX Pope Innocent VIII 1st blood transfusion - drank blood of 3 1o-yr old boys Braxton and Hicks (1869) Sodium phosphate as anticoagulant in blood units Dr. Charles Drew Director of American Red Cross Blood Bank 1914 Sodium citrate Loutit and Mollison (1943) ACD Gibson (1957) CPD Mary Mallon a cook who was a carrier of Salmonella typhi gallbladder organ that harbors S. typhi Susumu Tonegawa Nobel prize (1987) Antibody diversity (Genetic Principles underlying the generation of antibodies with different specificities) discovered in 1978 Ellie Metchnikoff phagocytosis Crew of Christopher Columbus contracted Syphilis to Europe Salt vaccine formalin killed polio vaccine -injected and stimulate ab prodxn in serum BUT NOT in mucosa Sabin Vaccine live attenuated polio virus vaccine -ORALLY administered and thus stimulate IgA and IgG prodxn 1984 discovery of T cell receptor (TcR) -associated with CD3 Chronic Granulomatous Disease (CGD) Respiratory Burst / Oxidative burst HLA - B27 ankylosing spondilitis / bamboo spine disease HLA-DR3 Systemic Lupus Erythematosus (SLE) HLA-DR4 Rheumatoid Arthritis (RA) HLA-B8 Myasthenia gravis (anti-acetylcholine ab) Addison's Disease Mixed Lymphocyte Reaction (MLR) Cellular method of tissue matching Microlymphocytotoxicity (serological approach) method in tissue typing which uses Inverted Phase Contrast chromosome 14 genetic coding of HEAVY cha