PIONEER ISBB PART 2 fully solved graded A+ 2023

PIONEER ISBB PART 2200-499/uL The CD4+ T lymphocyte count in Stage III HIV infection is: Inhibition A type of immunofluorescent assay that is a blocking test wherein the antigen is first exposed to unlabeled antibody, then to labeled antibody: Type I Hives and itching are examples of what type of hypersensitivity reaction? Early Acute Infection Interpret the following laboratory results: HBsAg = reactive HBeAg = reactive Anti-HBc = nonreactive Anti-HBe = nonreactive Anti-HBs = nonreactive 180 RPM for 4 minutes The rotation speed and time in the CSF VDRL test Strongly positive When using RF latex tests, a titer of 20-40 is considered as: 1. Binding 2. Blocking 4. Modulating There are three types of anti-acetylcholine receptor antibody. These are: Dirty glassware hemolyzed patient serum Which of the following are causes of false-positive technical errors? Enhancing proliferation of B cells Which represents the main function of IgD Viral infection Ferrata cells in exudates are indicative of: Do not issue the unit What should be done if a noticeable clot is found in an RBC unit? Need for special equipment Disadvantage of the gel technology: Dilute patient serum containing antibody, then repeat procedure What is the corrective action when prozone phenomenon occurs? Breast cancer CA 27.29 is a tumor marker used for detecting: rr What is one possible genotype for a patient who develops anti-C antibody? Deferroxamine An iron-chelating agent used to treat iron overload: Serum stored at 4°C for no longer than 48 hours What sample is best for detecting complement-dependent antibodies? Gregor Mendel He stated that genes come in pairs and are inherited one from each parent: Susumu Tonegawa He discovered the genetic principles underlying the generation of antibodies with different specificities: 30 days after exposure When should convalescent sera be obtained for diagnosis of rubella infection? Anti-E Which antibody is most likely to be involved in hemolytic disease of the newborn? 1:2, 1:6, 1:12 Which of the following serial dilutions contains an incorrect factor? IgG and IgM Nature of ABO antibodies: Activated partial thromboplastin time (APTT) A patient was tested for syphilis by the RPR method and was reactive. An FTA-ABS test was performed and the result was negative. Subsequent testing showed the patient to have a high titer of anticardiolipin antibodies (ACAs) by the ELISA method. Which routine laboratory test is most likely to be abnormal for this patient? To increase immunity To prevent kernicterus To compensate for anemia What is the primary purpose of exchange transfusion? 6.0 g/dL The minimum required total protein level for plasmapheresis donors is: Yes, for red cells only A 53-year old woman donates blood at her place of employment. She weighs 150 lbs and has a hemoglobin of 13 g/dL. She is currently on warfarin and Vitamin B12. Is she an acceptable donor? Blood substitute What are perfluorocarbons (PFC)? 5 minutes Centrifugation time for gel tube technology: Patient's cells + Ulex europaeus = no agglutination You are working on a specimen in the laboratory that you believe to be a Bombay phenotype. Which of the following reactions would you expect to see? Red cells forming a well-delineated pellet at the bottom of the tube In Gel tube technology, a negative reaction refers to: D-- Which of the following Rh phenotypes has the highest number of D antigen sites? Le(a+b+) The rarest Lewis phenotype is: 42 days Red blood cells stored in CPDA-2 blood bag would have a shelflife of: The terminal galactose in a 1-3 linkage to subterminal N-acetylglucosamine A type 1 chain has: Sd^a The antibody to this high-prevalence antigen demonstrates mixed-field agglutination that appears shiny and refractile under the microscope: To restore ATP and 2,3-DPG What is the purpose of adding rejuvenating solutions to RBC products? Well developed at birth, susceptible to enzymes, generally saline reactive Which of the following best describes MN antigens and antibodies? To prevent caramelization What is the purpose of adding citric acid to blood bag preservatives? 3 How many H antigen structures is (are) currently identified? Urine Anti-Sda has been identified in a patient. What substance would neutralize this antibody and allow detection of other alloantibodies? 6.5 to 7.5 The ideal pH for agglutination reaction is: Cesium 137 Which of the following can be used to irradiate blood components? frozen RBCs and cryoprecipitate What component(s) may be shipped together with FFP?