psy 365 exam 2 | 91 Questions and Answers(A+ Solution guide)

Primary marijuana psychoactive - THC Drug tests are looking for which marijuana metabolite? - THC-COOH. which is an inactive metabolite that excreted in urine, feces What breaks down THC? - Hepatic cytochrome breaks down THC. Cannabis sativa - Produces an energetic high, people feel happier, laughing. Cannabis indica - Produces a relaxing, numbness high, body high, increased taste and munchies Marijuana chemicals - There are about 60-85 psychoactive chemicals in marijuana. And about 400 in total. Marijuana routes of absorption - Inhalation(Smoking and Vaping) Oral(Edibles) Marijuana Inhalation - Takes about 30 seconds to get to the brain. Only absorbs 25-50% of the THC when using joints, pipes, bongs. Factors dictating marijuana high - How long you hold the smoke in your lungs and quality of drugs Marijuana oral absorption - THC is absorbed through the small intestine High takes about 1-2 hours to kick in4-6 hour high THC binds to? - Cannabinoid receptors How is THC metabolized? - Gets broken down by Hepatic cytochrome P450 THC half life - 19-30 hours. 20-30% still present a week later What is unique about THC metabolization? - THC can linger in the fat in the body for days to weeks. Hepatic cytochrome breaks down THC and then becomes an active metabolite. The THC-COH then makes it an inactive metabolite and eventually leaves the body through urinary tract. Marijuana overdose - Highly unlikely. There have been no reported cases. LSD overdose - Highly unlikely. No reported cases. Amotivational syndrome - Lack of motivation, laziness and goals as a result of chronic marijuana use