Chapter 11: The Cell Cycle and Cell Division

BIOL BIOL:1411 Test File Review Questions Life: The Science of Biology, Ninth Edition Chapter 11: The Cell Cycle and Cell Division TEST FILE QUESTIONS Multiple Choice 1. Which of the following is not true about cervical cancer, which is a relatively common cancer? a. It can be detected early by a PAP test. b. It is usually caused by human papillomavirus (HPV). c. It causes the cervical cells to make peptide E7, which disrupts the cell cycle. d. It spreads by blocking the retinoblastoma protein RB. e. It usually remains localized. Answer: e Textbook Reference: 11.0 An enemy of the cell reproduction cycle Page: 209–210 Bloom’s Category: 1. Remembering 2. A bacterial cell gives rise to two genetically identical daughter cells by a process known as a. nondisjunction. b. mitosis. c. meiosis. d. fission. e. fertilization. Answer: d Textbook Reference: 11.1 How Do Prokaryotic and Eukaryotic Cells Divide? Page: 210 Bloom’s Category: 1. Remembering 3. For a prokaryote cell to divide, which of the following must occur? a. A reproductive signal, replication, segregation of DNA, and cytokinesis b. DNA replication, crossing over, and segregation of DNA c. DNA replication and segregation of DNA d. Cell growth and cytokinesis e. DNA replication, segregation of DNA, and cytokinesis Answer: a Textbook Reference: 11.1 How Do Prokaryotic and Eukaryotic Cells Divide? Page: 210 Bloom’s Category: 2. Understanding 4. During the bacterial cell division, the single cells is separated into two cells by a. centrosomes. b. spindle fibers. c. nucleosomes. d. pinching of the plasma membrane. e. aneuploidy. Answer: d Textbook Reference: 11.1 How Do Prokaryotic and Eukaryotic Cells Divide? Page: 211 Bloom’s Category: 2. Understanding 5. During prokaryotic cell division, two chromosomes separate from each other and distribute into the daughter cells by a. attachment to microtubules. b. a mitotic spindle. c. repellent forces. d. attachment to separating membrane regions. e. All of the above Answer: d Textbook Reference: 11.1 How Do Prokaryotic and Eukaryotic Cells Divide? Page: 211 Bloom’s Category: 2. Understanding 6. Bacteria typically have , whereas eukaryotes have . a. one chromosome that is circular; many chromosomes that are linear b. several chromosomes that are circular; many chromosomes that are linear c. one chromosome that is linear; many chromosomes that are circular d. two chromosomes that are circular; eight chromosomes that are linear e. None of the above Answer: a Textbook Reference: 11.1 How Do Prokaryotic and Eukaryotic Cells Divide? Page: 211 Bloom’s Category: 2. Understanding 7. Which of the following statements about mitosis is true? a. The chromosome number in the resulting cells is halved. b. DNA replication is completed in prophase. c. Crossing over occurs during prophase. d. Two genetically identical daughter cells are formed. e. It consists of two nuclear divisions. Answer: d Textbook Reference: 11.1 How Do Prokaryotic and Eukaryotic Cells Divide? Page: 212 Bloom’s Category: 2. Understanding 8. DNA replication occurs a. during both mitosis and meiosis. b. only during mitosis. c. only during meiosis. d. during the S phase. e. during G2. Answer: d Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 1. Remembering 9. Mature nerve cells, which are incapable of cell division, are most likely in a. G1. b. the S phase. c. G2. d. mitosis. e. meiosis. Answer: a Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 3. Applying 10. A set of cells in the intestinal epithelium divide continually to replace dead cells lost from the surface of the intestinal lining. If you examined this continually dividing population of intestinal epithelial cells under the microscope, most of the cells would a. be in meiosis. b. be in mitosis. c. be in interphase. d. have condensed chromatin. e. Both b and d Answer: c Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 3. Applying 11. Cells that do not divide are usually arrested in a. S. b. G1. c. G2. d. M. e. prophase. Answer: b Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 1. Remembering 12. Which of the following phases of the cell cycle is not part of interphase? a. M b. S c. G1 d. G2 e. G0 Answer: a Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 1. Remembering 13. How does a nucleus in G2 differ from a nucleus in G1? a. The G2 nucleus has double the amount of DNA as the G1 nucleus. b. DNA synthesis occurs only in the G1 phase. c. Inactive cells are arrested only in the G2 phase. d. During G2, the cell prepares for S phase. e. All of the above Answer: a Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 2. Understanding 14. A typical cell cycle consists of a. mitosis and meiosis. b. G1, the S phase, and G2. c. prophase, metaphase, anaphase, and telophase. d. interphase, mitosis, and cytokinesis. e. meiosis and fertilization. Answer: d Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 213 Bloom’s Category: 1. Remembering 15. Regulation of the cell cycle is dependent on cyclins and cyclin-dependent kinases. The key(s) that allows a cell to progress beyond the restriction point is (are) a. Cdk1 and cyclin B. b. cyclin D and p21. c. cyclin A and Cdk2. d. phosphorylation of RB by Cdk4 and Cdk2. e. external signals from growth factors. Answer: d Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 214 Bloom’s Category: 2. Understanding 16. Evidence from yeast suggests that the maturation-promoting factor of sea urchins is a. a cyclin. b. MFP. c. an S nuclease. d. a Cdk. e. a Cdk/cyclin phosphatase. Answer: d Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 214 Bloom’s Category: 1. Remembering 17. The initiation of the S phase and the M phase of the cell cycle depends on a pair of molecules called and . a. actin; myosin b. Cdk’s; cyclin c. ligand; receptor d. MSH; MSH-receptor e. ATP; ATPase Answer: b Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 214 Bloom’s Category: 1. Remembering 18. When cyclin binds Cdk, a. the cell transitions from G2 to S. b. kinase activation occurs. c. chromosomes condense. d. the cell quickly enters M phase. e. the cell begins apoptosis. Answer: b Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 214 Bloom’s Category: 2. Understanding 19. Cyclin-dependent kinases (Cdk’s) catalyze the phosphorylation of targeted proteins, a process that a. decreases the mass of the protein. b. makes the targeted proteins hydrophobic. c. changes the shape and function of the targeted proteins. d. gives the proteins a three-dimensional shape. e. blocks the cell cycle from proceeding. Answer: c Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 214 Bloom’s Category: 2. Understanding 20. DNA damage by UV radiation causes the synthesis of a. p53. b. DNA. c. Cdk. d. cyclin. e. p21. Answer: e Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 215 Bloom’s Category: 1. Remembering 21. Interleukins and erythropoietin are a. growth factors. b. Cdk’s. c. cyclins. d. antitumor agents. e. intracellular signaling molecules. Answer: a Textbook Reference: 11.2 How Is Eukaryotic Cell Division Controlled? Page: 215 Bloom’s Category: 1. Remembering 22. The DNA of a eukaryotic cell is a. double-stranded. b. single-stranded. c. circular. d. complex inverted. e. conservative. Answer: a Textbook Reference: 11.3 What Happens during Mitosis? Page: 215 Bloom’s Category: 1. Remembering 23. The uncondensed length of human DNA found in chromosomes is , whereas a typical cell is 10 µm in length. a. 5 µm b. 2 µm c. 2 meters d. 20 meters e. 2.54 inches Answer: c Textbook Reference: 11.3 What Happens during Mitosis? Page: 216 Bloom’s Category: 1. Remembering 24. Chromosomes contain large amounts of interacting proteins known as a. pentanes. b. hexosamines. c. histones. d. protein hormones. e. histamines. Answer: c Textbook Reference: 11.3 What Happens during Mitosis? Page: 216 Bloom’s Category: 1. Remembering 25. The molecules that make up a chromosome are and . a. DNA; RNA b. DNA; proteins c. proteins; lipids d. nucleotides; nucleosides e. proteins; phospholipids Answer: b Textbook Reference: 11.3 What Happens during Mitosis? Page: 216 Bloom’s Category: 2. Understanding