Rapid Review USMLE Step 2 CK - Hematology/Oncology Exam Solved 100%

Four causes of microcytic anemia - Answer TICS: Thalassemia Iron-deficiency anemia Chronic disease Sideroblastic anemia Elderly man with hypochromic, microcytic anemia is asymptomatic. Diagnostic tests? - Answer Suspect colorectal cancer: Fecal occult blood test Sigmoidoscopy Precipitants of hemolytic crisis in patients with G6PD deficiency - Answer Sulfonamides Antimalarial drugs Fava beans Most common inherited cause of hypercoagulability - Answer Factor V Leiden mutation Most common inherited bleeding disorder - Answer von Willebrand disease Most common inherited hemolytic anemia - Answer Hereditary spherocytosis Diagnostic test for hereditary spherocytosis - Answer Osmotic fragility test Pure RBC aplasia - Answer Diamond-Blackfan anemia Anemia associated with absent radii and thumbs, diffuse hyperpigmentation, cafe au lait spots, microcephaly, and pancytopenia - Answer Fanconi anemia Medications and viruses that lead to aplastic anemia - Answer Chloramphenicol Sulfonamides Chemotherapeutic agents Radiation Hepatitis Parvovirus B19 HIV EBV Distinguish polycythemia vera from secondary polycythemia - Answer Both have increased hematocrit and RBC mass Polycthemia vera should have normal O2 saturation and low EPO levels Thrombotic thrombocytopenic purpura (TTP) pentad - Answer FAT RN: Fever Anemia Thrombocytopenia Renal dysfunction Neurologic abnormalities