Clinical Chemistry-TDM Questions With Complete Solutions

Which of the following compounds is an anticonvulsant used to control tonic-clonic (grand mal) seizures? correct answer: Phenytoin To achieve "steady state", a drug should be administered _________ correct answer: every time it reaches half-life Following the entrance of a drug into the vascular compartment, it will be carried to all organs and fluid compartments. This statement describes which of the following? correct answer: Distribution Which route of administration bypasses the first phase of drug processing? correct answer: IV injection The pharmacological response of drug is initiated when the drug is in which form? correct answer: Free Giving Gentamicin over the minimum toxic concentration can cause ______________ in newborns. correct answer: deafness Phenobarbital is classified as a: correct answer: Sedative and hypnotic. Which of the following is an example of an antiarrhythmic drug that has a metabolite with the same pharmacological action? correct answer: Procainamide What is the drug of choice to treat MRSA? correct answer: vancomycin Which of the following is a xanthene that potentially could interfere with the determination of theophylline? correct answer: Caffeine If a drug is metabolized in first order kinetics correct answer: the higher the drug concentration the faster the liver metabolizes it Which of the following is bacterialcidal for Streptococci, Corynebacteria, Clostridia, Listeria, and Bacillus species?