MLT Clinical Chemistry Final| 200 Questions | With Complete Solutions

Enzymes that can bind only one substrate and catalyze one reaction exhibit which type of binding specificity? correct answer: Absolute binding The rate of an enzymatic reaction will ___________________ for every 10 degrees C temperature increase until the enzyme denatures. correct answer: Double All of the following conditions may result in a rise in CKBB levels except. a. Child birth b Spinal chord injury c. Myocardial infarction d. Brain tumor correct answer: c. Myocardial infarction Which two enzymes will show significant elevations with viral hepatitis? correct answer: AST & ALT GGT is an enzyme that can be used to help monitor the treatment of which patient population? correct answer: recovering alcoholics Digestive enzymes circulate in inactive forms called __________________. correct answer: Zymogens A patient comes to the ER with abdominal pain, the physician ordered an amylase, lipase, and lipid panel. The triglyceride result is significantly elevated, how might this effect the amylase and lipid levels? (thrown out) correct answer: Unchanged lipase, decreased amylase Which of the following is a function of glucose-6-phosphate dehydrogenase (G6PD) a. prevents RBC lysis b. inhibits CK c. stimulates insulin secretion d. catalyzes the conversion of glutamate correct answer: a. prevents RBC lysis Which type of enzyme kinetics assay is ideal fro the clinical laboratory setting where the amount of enzyme produced by the patient is unknown? correct answer: zero order What condition is characterized by elevated serum amylase levels and decrease urinary amylase levels due to amylase binding to immunoglobulins? correct answer: macroamylasemia In the presence of a competitive inhibitor, what would need to be increased to reach VMax? correct answer: substrate