Elsevier: Clinical Chemistry Questions
With Complete Solutions
1. Which of the following is considered a lipid?
a. Chylomicrons b. LDL
c. Cholesterol d. HDL correct answer: c
2. In the laboratory procedure for the quantification of HDL, the purpose of the dextran sulfate is to: a. Precipitate all Apo A1 containing lipoproteins
b. Covert cholesterol esters to cholesterol for detection c. Precipitate all Apo B and Apo A containing lipoproteins d. Precipitate all Apo B containing proteins correct answer: d
Which of the following lipoproteins is the smallest of all the lipoproteins and is composed of 50% protein? a. HDL b. Chylomicrons c. LDL d. Triglycerides correct answer: A
Which of the following would be most adversely affected by a nonfasting sample? a. HDL b. LDL c. Cholesterol d. Triglycerides correct answer: d
Which of the following apoproteins is responsible for receptor binding for IDL and the chylomicron remnant produced in fat transport? a. Apo A1 b. Apo C c. Apo E d. Apo B correct answer: c
Which of the following enzymes is found bound to HDL and LDL in blood plasma and acts to convert free cholesterol into cholesteryl esters? a. Cholesterol esterase b. Cholesterol oxidase c. Lecithin-cholesterol acyltransferase d. Lipase correct answer: c
Which of the following blood samples would serve best to assay
lipoproteins because this anticoagulant acts to preserve lipoproteins? a. EDTA plasma sample b. Heparin plasma sample c. Citrate plasma sample d. Fluoride plasma sample correct answer: a Exogenous triglycerides are transported in the plasma in which of the following forms? a. VLDL b. Chylomicrons c. LDL d. Cholesteryl esters correct answer: b
A patient presents to his physician for a lipid profile. The following results are received: HDL¼50 mg/dL Total cholesterol¼300 mg/dL Triglycerides¼200 mg/dL The calculated LDL cholesterol is: a. 200 b. 210 c. 290 d. 350 correct answer: b
According to the National Cholesterol Education Program, which lipid or lipoprotein class is more important for therapeutic
decision making (diet and medication decisions)?
a. Chylomicrons b. LDL c. HDL d. Cholesterol correct answer: b
Which of the following mechanisms accounts for the elevated plasma level of b-lipoproteins seen in hyperbetalipoproteinemia (Fredrickson's type II lipoproteinemia)? a. Elevated insulin found in these patients b. Apo B-100 receptor defect
c. Apo C-II-activated lipase deficiency d. LCAT deficiency correct answer: b
Which enzyme is common to all enzymatic methods for triglyceride measurement? a. Glycerol phosphate oxidase b. Glycerol phosphate dehydrogenase c. Pyruvate kinase d. Glycerol kinase correct answer: d
A patient sample is assayed for fasting triglycerides and a triglyceride value of 1036 mg/dL. This value is of immediate concern because of its association with which of the following conditions? a. Coronary heart disease b. Diabetes c. Pancreatitis d. Gout correct answer: c
Which of the following apoproteins is inversely related to risk for coronary heart disease and is a surrogate marker for HDL? a. Apo A-I b. Apo B c. Apo B100 d. APO E correct answer: a
With Complete Solutions
1. Which of the following is considered a lipid?
a. Chylomicrons b. LDL
c. Cholesterol d. HDL correct answer: c
2. In the laboratory procedure for the quantification of HDL, the purpose of the dextran sulfate is to: a. Precipitate all Apo A1 containing lipoproteins
b. Covert cholesterol esters to cholesterol for detection c. Precipitate all Apo B and Apo A containing lipoproteins d. Precipitate all Apo B containing proteins correct answer: d
Which of the following lipoproteins is the smallest of all the lipoproteins and is composed of 50% protein? a. HDL b. Chylomicrons c. LDL d. Triglycerides correct answer: A
Which of the following would be most adversely affected by a nonfasting sample? a. HDL b. LDL c. Cholesterol d. Triglycerides correct answer: d
Which of the following apoproteins is responsible for receptor binding for IDL and the chylomicron remnant produced in fat transport? a. Apo A1 b. Apo C c. Apo E d. Apo B correct answer: c
Which of the following enzymes is found bound to HDL and LDL in blood plasma and acts to convert free cholesterol into cholesteryl esters? a. Cholesterol esterase b. Cholesterol oxidase c. Lecithin-cholesterol acyltransferase d. Lipase correct answer: c
Which of the following blood samples would serve best to assay
lipoproteins because this anticoagulant acts to preserve lipoproteins? a. EDTA plasma sample b. Heparin plasma sample c. Citrate plasma sample d. Fluoride plasma sample correct answer: a Exogenous triglycerides are transported in the plasma in which of the following forms? a. VLDL b. Chylomicrons c. LDL d. Cholesteryl esters correct answer: b
A patient presents to his physician for a lipid profile. The following results are received: HDL¼50 mg/dL Total cholesterol¼300 mg/dL Triglycerides¼200 mg/dL The calculated LDL cholesterol is: a. 200 b. 210 c. 290 d. 350 correct answer: b
According to the National Cholesterol Education Program, which lipid or lipoprotein class is more important for therapeutic
decision making (diet and medication decisions)?
a. Chylomicrons b. LDL c. HDL d. Cholesterol correct answer: b
Which of the following mechanisms accounts for the elevated plasma level of b-lipoproteins seen in hyperbetalipoproteinemia (Fredrickson's type II lipoproteinemia)? a. Elevated insulin found in these patients b. Apo B-100 receptor defect
c. Apo C-II-activated lipase deficiency d. LCAT deficiency correct answer: b
Which enzyme is common to all enzymatic methods for triglyceride measurement? a. Glycerol phosphate oxidase b. Glycerol phosphate dehydrogenase c. Pyruvate kinase d. Glycerol kinase correct answer: d
A patient sample is assayed for fasting triglycerides and a triglyceride value of 1036 mg/dL. This value is of immediate concern because of its association with which of the following conditions? a. Coronary heart disease b. Diabetes c. Pancreatitis d. Gout correct answer: c
Which of the following apoproteins is inversely related to risk for coronary heart disease and is a surrogate marker for HDL? a. Apo A-I b. Apo B c. Apo B100 d. APO E correct answer: a
