USMLE Step 1 High Yield Images (Part 1-9) Questions With Correct Answers

Oligodendrocytes Myelinating cells of CNS "fried egg" - Answer Drusen bodies Spotty white/yellow material in eye Age related macular degeneration - Answer Achilles tendon xanthoma [AD] Familial hypercholesterolemia (no LDL R) - Answer Cherry hemangioma Adult, benign - Answer Roth spots Retinal hemorrhage w pale center Bacterial endocarditis - Answer Keyser-Fleischer Ring Wilson's dz= Low ceruoplasmin Cu accumulation KF ring present= Basal Ganglia atrophy as well - Answer Corneal arcus LDL deposits common in elderly= Arcus sinelis - Answer "Cherry-red spots" on macula Niemann-Pick (+HSM)-- sphingomylin Tay-Sachs (-HSM) -- small gang of 6 jews Central retinal A. occlusion (not vein, V. = "Blood + Thunder") - Answer Lisch nodules NF1 q17 (neurofibromatosis type 1) =von recklinghausen disease vs NF2 q22 (bilat acoustic neuromas) - Answer Erythema infectiosum "Slapped cheek dz"= fifth disease Parvovirus B19 -- only ssDNA virus on Boards (causes acute arthropy in adults) - Answer Kaposi's sarcoma HHV8, AIDS dr atchley: Kaposi sarcoma CD4<400 HHV8 Lymphocyte Bacillary Angiomatosis CD4<50 PMN (neutrophils)/mixed Neutrophils BOTH= red/purple raised skin lesions & angioproliferative - Answer Burton lines Pb poisoning (basophilic stippling on blood smear) - Answer Henoch-Schonlein Purpura child w/ palpable purpura s/p URI, type 3 HSR, IgA (as is PAN,type 3 HSR, p-ANCA think HBV sAg) - Answer Currant jelly sputum PNA from Klebsiella Pneumoniae - Answer Cryptococcus neoformans India ink-- polysaccharide capsule, pigeon droppings (Cities) - Answer Gumma 3' syphilis - Answer Port-Wine Stain (Nevus Flammeus) Sturge Webber syndrome also have ipsilat AV malformation Sturge-WEBer --> Affects capillary webs (sporadic mutate GNAQ not [AD]) Facial capillaries (port-wine stain) Leptomeningeal capillaries (angioma)= Sz, intellect disability Scleral capillaries (scleral angioma)= Early glaucoma - Answer Erythema chronicum migrans "bulls-eye rash" Lyme dz= borrelia burgdorferi, Ixodes tick: 1- Lyme dz= borrelia burgdorferi 2- Babiesosis (Maltese cross) in USA (VS malaria= ring shape) - Answer Subdural hematoma Crescent shape, Bridging vein Elderly blunt head trauma/shaky baby - Answer Bouchard's nodes OA @ PIP= Bouchard nodes (B before H) @ DIP= Heberden nodes (B before H)) - Answer Splinter hemorrhages bacterial endocarditis - Answer PSaMMoma Bodies (Ca+) Papillary thyroid CA + orphan Annie eyes Serous cystadenoCA (ovary/endometrium) Meningioma Mesothelioma - Answer Howell-Jolly bodies DNA in RBC Asplenia or functionally splenic (HbSS) - Answer Ankylosing Spondylitis HLA-B27 - Answer Curshmann spirals Asthma (mainly asthma) - Answer Koplik spots= red spot inner cheek Measles (Rubeola)-- 3 C's= cough, coryza, conjunctivitis diff than Rubella (German measles)--Forchheimer spots= (white/salt granules) on soft palate - Answer Condyloma lata 2' Syphilis PAINLESS white lesions diff that condyloma acuminata= HPV (6+11), 16+18= CA 1' Syphilis= Chancre (painless) 2' Syphilis= Condyloma Lata 3' Syphilis= Gumma - Answer Gaucher cell "tissue paper" lipid layden macrophage "crumpled up tissue paper" Gaucher dz (LSD) *GlucocereBROsidase defeciency* *GlucocereBROside buildup (toxic)* "oh my Gauch he's such a bro-ken bone" femoral head osteonecrosis - Answer Lichen Planus 5 P's= Purple Planar Polygonal Pruritic Papules - Answer Hutchinson teeth Congenital Syphilis - Answer Charcot-Leyden crystals Aggregates of Major basic proteins (from eosinophils) Asthma= Charcot leyden crystals + Curshman spirals - Answer Epidural hematoma "Lens shape" Middle meningeal A., traumatic skull fx, lucid interval - Answer Auer rods= AML specifically APML= t(15;17) MPO+ (myeloperoxidase) Tx: All Trans Retinoic Acid (vit. A) - Answer Histoplasmosis fungi in macrophage *Ohio/Mississippi River valley *spelunker, cave/bat - Answer Heberden nodes OA @ PIP= Bouchard nodes (B before H) @ DIP= Heberden nodes (B before H) - Answer Kimmelstiel-Wilson nodules *DM nephropathy (thick GBM, mesangial expansion) - Answer Dermatitis herpetiformis *Celiac dz GI sx + rash think celiac - Answer Burkitt lymphoma "stary sky" appearance EBV t(8;14) c-myc "Burk-myc" lymphoma - Answer Basophilic stippling Pb poisoning or sideroblastic anemia (MCC sideroblastic anemia= alcoholic) - Answer Glioblastoma "GPM" GFAP+ Pseudopalisading necrosis Midline/malignant - Answer Hyaline cast dehydrated Goljan= proteinurea or not clinically significant - Answer