With Complete Solutions
Hemoglobin correct answer: Tetramer of two alpha and two
beta polypeptide chains
Contains heme
Globin is a protein
Which amino acid change is involved in sickle cell anemia?
correct answer: Glu6Val
A single amino acid change in the beta chain of hemoglobin
causes sickle cell anemia
HbS forms long polymers that change the shape of the RBC
Where are hydrophobic and hydrophilic amino acids usually
found in a protein? correct answer: Hydrophobic on the inside
(non-polar interior)
Hydrophilic on the outside (interacts with polar solvent on the
protein surface)
What does sucrase do? correct answer: Breaks down sucrose
into glucose and fructose through a hydrolysis reaction
Which is more stable? AT or CG? correct answer: CG is more
stable bc 3 hydrogen bonds
, AT only has 2
Resonance structures give the C-N bond in peptide backbones....
correct answer: Partial double bond character
Sometimes the N holds two electrons
Sometimes they share it in a double bond
Characteristics of peptide bond? correct answer: Planar
Trans conformation of the carbonyl O and amide H
What is the phi angle? correct answer: Angle around the alpha
carbon-amide nitrogen bond
What is the psi angle? correct answer: Angle around the alpha
carbon-carbonyl carbon bond
What is the omega angle? correct answer: Angle between the
peptide bond, N and the C
Ideal phi-psi angles for alpha helix? correct answer: (60, -50)
Ideal phi-psi angles for beta sheet? correct answer: (-140, 135)
What is a dihedral angle? correct answer: Angle between two
planes
What is a Ramachandran plot? correct answer: Plots all residues
on the axes of phi and psi