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Summary OCR A-Level Biology - Enzymes

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Hand-written summary notes using Seneca on the whole of Enzymes in Module 2 - Foundations in biology, OCR A-Level Biology (H420). This includes an overview on enzyme action; enzyme models; factors affecting enzyme activity; cofactors; inhibitors. Happy revising! :)

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August 10, 2023
Number of pages
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Written in
2022/2023
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enzymes




Contents:
• Enzyme Action
• Enzyme Models
• Factors Affecting Enzymes
• Cofactors
• Inhibitors

, Enzyme Action



earzyme function
Metabolism is the different processes thattake place in
living organisms to allow them to

survive




enzymes are proteins thatactas biological catalysts to speed up reactions in living
organisms
eg) Rubisco in plantcells catalyses the fixation ofcarbon dioxide in photosynthesis
eq) amylase in saliva catalyses the break down starch
of to
sugars when eating


enzymes can speed up reactions affecting organisms on the cellular and individual

Level

eg) enzymes catalysing photosynthes cells,
within produces products (fixed carbon

thatcan be used around plants on the organismal level to grow roots and

ShOOtS

enzymes can speed up reactions that
affectstructure and function
eg) enzymes catalyse production ofthe structural protein, collagen, in bones

eq) enzymes catalyse the respiration produces
reaction that ATP




lock and key model
fitmoder
induced

lock and key model proposes enzymes induced fitmodel suggests there is a

and substrates fit together perfectly more
dynamic interaction between enzyme
and substrate

origional model to
enzyme
explain
action newer, more
widely accepted model to

substrate is a key fitting into a explain enzyme action

Lock cenzymel enzyme and substrate interaction when

coming together causes a small shiftin
enzyme substrate product the enzymes structure

shift allows enzyme and substrate to


⑧ ⑲
a
form an E-S complex
bind to and

catalyse a reaction



enzyme substrate product
changes shape





enzyme-substrate complexes

enzymes only catalyse one specific reaction

each enzyme has specific active site thatis the specific substrate
a
complementary to

thatitforms an E-s with
complex
3D, tertiary structure ofthe polypeptide chain determines the shape ofthe active site



denatured enzymes occur when environmental changes cause the tertiary structure

ofthe active site to change, stopping the enzyme from working properly
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