NBME Sample Questions With Correct Answers - Latest Update 2023/2024 (100% Verified)

A 25-year-old man is brought to the emergency department because of a 6-day history of fever, severe muscle pain, and diffuse, painful swelling of his neck, underarms, and groin area. The symptoms began after returning from a camping trip in New Mexico. He appears ill and lethargic and can barely answer questions. His temperature is 39.2°C (102.5°F), pulse is 120/min, respirations are 22/min, and blood pressure is 110/70 mm Hg. Physical examination shows generalized scattered black maculae. Examination of the right upper extremity shows an erythematous, solid, tender mass on the underside of the upper extremity just above the elbow; the mass is draining blood and necrotic material. The most effective antibiotic for this patient's disorder will interfere with which of the following cellular processes or enzymes? - Answer DX:ulceroglandular Tularemia Tx with Aminoglycosides which target the 30S ribosomal unit The effects of excess thyroid hormone: - Answer attempted compensatory TSH suppression, increase in both T4 and free T4, and normal TBG Know - Answer rate-limiting metabolic pathways ive and negative feedback ng pathways opposing pathway for glycolysis - Answer gluconeogenesis Glycolysis - Answer the breakdown of glucose by enzymes to form pyruvate into ATP Glycolysis rate limiting enzyme - Answer Phosphofructokinase-1(PFK-1) Gluconeogenesis - Answer The formation of glucose from noncarbohydrate sources Gluconeogenesis rate-limiting enzyme - Answer Fructose-1,6-bisphosphatase Glycolysis is activated by four things - Answer 1.Glucose 2.Insulin 3.AMP ose 2,6 biphosphate proceed down from glucose to pyruvate/ATP Vincristine (a mitosis inhibitor) - Answer frequently causes peripheral neuropathy, which can be severe and irreversible. Open labeled clinical trial? - Answer When Both researchers and participants know which treatment is being administered Vincristine (a mitosis inhibitor) - Answer frequently causes peripheral neuropathy, which can be severe and irreversible. Bleomycin - Answer pulmonary fibrosis, hyperpigmentation Doxorubicin - Answer dilated cardiomyopathy Cholinesterase inhibitors (also called acetylcholinesterase inhibitors) - Answer are a group of medicines that block the normal breakdown of acetylcholine. Acetylcholine - Answer neurotransmitter chemical released at the ends of nerve cells and has functions in both the peripheral nervous system and the central nervous system. While professional competence is a cause - Answer people love to discuss and the boards love to test about poor physician communication and lack of empathy as root causes. awakened from sleep by shortness of breath. Her pulse is 96/min and regular, respirations are 24/min, and blood pressure is 128/76 mm Hg. Jugular venous pressure is 15 cm H2O. Pulmonary examination shows crackles at both lung bases. Cardiac examination shows a regular rhythm and a soft S3. A grade 3/6 holosystolic murmur is heard best at the apex, radiating to the axilla. There is 2+ pitting edema of the lower legs and ankles. DX: - Answer heart failure 2/2 mitral valve regurgitation. If we want to prove the regurg, we can confirm and grade it using an echo.* heart failure 2/2 mitral valve regurgitation DX - Answer can be confirmed by echocardiogram Pubertal gynecomastia - Answer is normal and generally goes away on its own. If "normal" is an answer choice Neutrophils - Answer should undergo an oxidative burst when exposed to S. aureus Respiratory burst (sometimes called oxidative burst) - Answer is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells which kills bacterial cells Relationship with former patients s. - Answer are generally frowned on, but they're especially problematic if the patient was a psychiatric patient, as the power imbalance of the practitioner-patient relationship and information the provider is privy to because of their patient care involvement preclude a healthy balanced relationship of equals. Subacute combined degeneration (progressive peripheral sensory and motor loss) - Answer Subacute combined degeneration (progressive peripheral sensory and motor loss) is a late sign of B12 deficiency, which is common in elderly people. On exams, a geriatric patient who lives alone and may have a "tea and toast" diet - Answer is likely to have vitamin deficiencies, particularly of folate and B12. A - The infraspinatus and teres minor - Answer are responsible for external rotation. Both the infraspinatus and supraspinatus muscles - Answer are innervated by a suprascapular nerve. infraspinatus - Answer supraspinatus - Answer sudden, intense feeling of overwhelming fear. Which of the following areas of the brain was most likely stimulated at that time? - Answer Amygdala