Psychopharmacology (Drugs and Behavior ) questions with correct answers

What are the four criteria for neurotransmitter (NT) identification? - Answer Chemical (as well as the enzymes responsible for its synthesis and catabolism) must be present in the presynaptic terminal of pathway examined • Chemical must be released from the examined pathway upon electrical and/or normal stimulation of cell • The exogenous placement of the chemical onto adjacent cell should mimic effects produced by natural or electrical stimulation of secreting cell • Compounds that block effects of the naturally or electrically stimulated release of NTs on adjacent cell should affect suspected chemical in similar fashion Where in the synapse drug can produce their effects? Describe five possible sites of action. - Answer Pre-synaptic Synthesis Vesicles Post Synaptic receptors Synaptic cleft Autoreceptors 3. Name monoamine neurotransmitters and explain why they are called such. How are monoamines are grouped into separate classes? - Answer They named so because they are made up of one amino group that is connected to an aromatic ring by a two-carbon chain (-CH2-CH2- Dopamine Norepinephrine Epinephrine Serotonin