PEDIATRIC CALCULATIONS
Discuss why children require different dosages of drugs than adults. Explain the calculations used to determine a safe pediatric dose of a drug. NN PEDIATRIC CONSIDERATIONS An adult’s body handles drugs differently and may respond to drugs differently than a child. A child’s body may handle a drug differently in all areas of pharmacokinetics—absorption, distribution, metabolism, and excretion. NN PEDIATRIC CONSIDERATIONS The responses of the child’s organs to the effects of the drug may vary because of the immaturity of the organs. Most of the time a child requires a smaller dose of a drug to achieve the comparable critical concentration as that for an adult. NN FRIED'S RULE A calculation method that applies to a child younger than 1 year of age. The rule assumes that an adult dose would be appropriate for a child who is 12.5 years (150 months) old. NN FRIED'S RULE NN PROBLEM # 1 If an adult dose of a particular medication is 50 mg, what is the dosage of a 10 months old infant? NN SOLUTION NN PROBLEM # 2 Calculate the dose for a 1 year old baby, wher
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