WGU D115 Distributed Formative
Assessment 3 Latest 2023
A patient presents to an advanced practice registered nurse (APRN) complaining of
diarrhea, rectal bleeding, and right lower quadrant tenderness. Diagnostic tests reveal
deficiencies in folic acid, vitamin D, and calcium. The APRN suspects Crohn disease.
What is the pathological mechanism of this disorder?
Neutrophil infiltration of the crypts, which causes destructive abscess formation
Destruction of mucosal barrier caused by drugs or Helicobacter pylori infection
Acid and pepsin in the duodenum penetrating the mucosal barrier, which causes
ulceration
Decreased mucosal blood flow and hypersecretion of acid caused by overstimulation of
the vagal nuclei - ✔Crohn disease can involve any part of the gastrointestinal tract from
the oropharynx to the perianal area. Diseased segments frequently are separated by
intervening normal bowel, leading to the term "skip areas." Inflammation can be
transmural, often extending through to the serosa, resulting in sinus tracts or fistula
formation.
A patient with a history of prostate cancer is admitted with confusion, thirst, nausea,
oliguria, and abdominal cramping. The patient has gained 12 lb in the last two weeks.
Diagnostics include
potassium: 4.1 mEq/L
sodium: 118 mEq/L
serum osmolality: 272 mOsm/kg H2O
increased urine osmolality
Which part of the nephron is affected by this endocrine disorder?
Distal tubule and collecting duct
Proximal tubule and descending loop
Glomerular capsule
Bowman capsule - ✔Syndrome of inappropriate secretion of antidiuretic hormone (ADH)
is an over secretion of ADH by the posterior pituitary gland due to several reasons,
Assessment 3 Latest 2023
A patient presents to an advanced practice registered nurse (APRN) complaining of
diarrhea, rectal bleeding, and right lower quadrant tenderness. Diagnostic tests reveal
deficiencies in folic acid, vitamin D, and calcium. The APRN suspects Crohn disease.
What is the pathological mechanism of this disorder?
Neutrophil infiltration of the crypts, which causes destructive abscess formation
Destruction of mucosal barrier caused by drugs or Helicobacter pylori infection
Acid and pepsin in the duodenum penetrating the mucosal barrier, which causes
ulceration
Decreased mucosal blood flow and hypersecretion of acid caused by overstimulation of
the vagal nuclei - ✔Crohn disease can involve any part of the gastrointestinal tract from
the oropharynx to the perianal area. Diseased segments frequently are separated by
intervening normal bowel, leading to the term "skip areas." Inflammation can be
transmural, often extending through to the serosa, resulting in sinus tracts or fistula
formation.
A patient with a history of prostate cancer is admitted with confusion, thirst, nausea,
oliguria, and abdominal cramping. The patient has gained 12 lb in the last two weeks.
Diagnostics include
potassium: 4.1 mEq/L
sodium: 118 mEq/L
serum osmolality: 272 mOsm/kg H2O
increased urine osmolality
Which part of the nephron is affected by this endocrine disorder?
Distal tubule and collecting duct
Proximal tubule and descending loop
Glomerular capsule
Bowman capsule - ✔Syndrome of inappropriate secretion of antidiuretic hormone (ADH)
is an over secretion of ADH by the posterior pituitary gland due to several reasons,
