UNE Biochem MIDTERM Questions With
Complete Solutions
α-helices and β-sheets are primarily stabilized by which of the
following interactions? correct answer: hydrogen bonding
Domains are common structural elements that retain a particular
function within the protein. Which of the following is an
example of a protein domain? correct answer: An arrangement
of β-strands connected by α-helices (βαβαβ)
How do most enzymes reduce the activation energy needed to
move a reaction forward? correct answer: Providing an active
site most complementary the transition state
A 22-year old female presents to the emergency department with
acute abdominal pain. She indicates the pain came on rapidly in
her mid-abdominal region. She has vomited several times over
the last 4 hours. A diagnosis of acute pancreatitis is made and
she is rushed to surgery. Elevation of which of the following
serum enzymes would be consistent with this diagnosis? correct
answer: amylase
Cleavage of fructose 1, 6-bisphosphate to dihydroxyacetone and
glyceraldehyde 3-phosphate is achieved by what class of
enzymes? correct answer: lyase
, Chymotrypsin is a protease that cleaves peptide bonds. It is
characterized as which of the following classes of enzymes?
correct answer: hydrolases
Which of the following best describes tertiary structure? correct
answer: Interactions between α-helices and β sheets to form a
domain
An α-helical arrangement of amino acids is considered to be
what level of protein structure? correct answer: secondary
structure of the protein
An example of enzyme activation by cleavage is best illustrated
by which of the following? correct answer: Activation of
chymotrypsinogen to chymotrypsin
In the image below the blue line indicates enzyme kinetics with
no inhibitor present. Based on this information which of the
following is true? correct answer: The green line shows enzyme
kinetics with the addition of a noncompetitive inhibitor
A new enzyme is discovered that increases in activity when it is
phosphorylated on an exposed tyrosine residue. Phosphorylation
of this amino acid is classified as which of the following?
correct answer: Covalent modification
A 28-year-old male is recently diagnosed with HIV. As part of
his treatment he is prescribed Nevirapine which interferes with
retroviral reverse transcriptase enzyme. Using the graph below,
which of the following best describes the impact of this drug on
Complete Solutions
α-helices and β-sheets are primarily stabilized by which of the
following interactions? correct answer: hydrogen bonding
Domains are common structural elements that retain a particular
function within the protein. Which of the following is an
example of a protein domain? correct answer: An arrangement
of β-strands connected by α-helices (βαβαβ)
How do most enzymes reduce the activation energy needed to
move a reaction forward? correct answer: Providing an active
site most complementary the transition state
A 22-year old female presents to the emergency department with
acute abdominal pain. She indicates the pain came on rapidly in
her mid-abdominal region. She has vomited several times over
the last 4 hours. A diagnosis of acute pancreatitis is made and
she is rushed to surgery. Elevation of which of the following
serum enzymes would be consistent with this diagnosis? correct
answer: amylase
Cleavage of fructose 1, 6-bisphosphate to dihydroxyacetone and
glyceraldehyde 3-phosphate is achieved by what class of
enzymes? correct answer: lyase
, Chymotrypsin is a protease that cleaves peptide bonds. It is
characterized as which of the following classes of enzymes?
correct answer: hydrolases
Which of the following best describes tertiary structure? correct
answer: Interactions between α-helices and β sheets to form a
domain
An α-helical arrangement of amino acids is considered to be
what level of protein structure? correct answer: secondary
structure of the protein
An example of enzyme activation by cleavage is best illustrated
by which of the following? correct answer: Activation of
chymotrypsinogen to chymotrypsin
In the image below the blue line indicates enzyme kinetics with
no inhibitor present. Based on this information which of the
following is true? correct answer: The green line shows enzyme
kinetics with the addition of a noncompetitive inhibitor
A new enzyme is discovered that increases in activity when it is
phosphorylated on an exposed tyrosine residue. Phosphorylation
of this amino acid is classified as which of the following?
correct answer: Covalent modification
A 28-year-old male is recently diagnosed with HIV. As part of
his treatment he is prescribed Nevirapine which interferes with
retroviral reverse transcriptase enzyme. Using the graph below,
which of the following best describes the impact of this drug on
