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Summary AQA ALEVEL BIOLOGY NOTES CELL MEDIATED RESPONSE

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ALEVEL NOTES ON THE IMMUNITY TOPIC- CELL MEDIATED REPONSE ADJUSTED TO THE AQA SPECIFICATION AND MADE FROM MARKSCHEMES

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July 2, 2023
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2022/2023
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Cell-mediated Response
=

Basics
Immunity
, IH4N a"




what ?
are
antigens



An antigen is
part of substance that is
recognised self lforeign)
any an
organism or as non -




by the immune and stimulates immune
system an
response .




'


Antigens are
usually proteins that are part of the cell -
surface membranes or cell walls of invading
cells such such
,
as
microorganisms ,
or abnormal body cells ,
as cancer cells .




Cell-mediated immunity involved T
lymphocytes
-




called
T
lymphocytes so because they mature in the
thymus gland
'

are .




-
Cell-mediated immunity is
immunity involving body cells .




Cell -
mediated Immunity
1-
%
,"



have different cell surface membrane from the
Foreign cells
antigens their antigens on the
'

on
-




's cells
organism own .




What are
antigen -


presenting cells ?


surface
Antigen presenting cells are cells that
display foreign antigens their
'
-

on .




'


These cells can present antigens of other cells on their own cell -
surface membrane .




cells
Antigen presenting -




Phagocytes that have
engulfed and
hydrolysed pathogen present of
pathogen 's


a some a
antigens
on their own cell -
surface membrane

cells invaded of their surface
Body by a virus present some the viral
antigens own cell
. -
on



membrane .




from have different their
-


Transplanted cells individuals of the same species antigens on



cell surface -
membrane .




different from
Cancer cells are normal
body cells and present antigens their
-

on



cell -
surface membranes .




Neutrophils lthagooyte )

Account for around 60% of the white blood cells .




Part of of terms
cells
granulocytes


a
group .




( have
Polymorphs lobed



. nuclear a nucleus)


They have short lifespan and travel the blood


a in .




Macrophages cphagocyte )

Tend to live inside tissues .





when
they ingest a
phathogen ,
they will begin
to display the
pathogens antigens on their surface
'' "
membrane the respond This Presentation
-
this stimulates
lymphocytes to
.


process is called
Antigen .
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