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Biology of Cancer Week 11 Lecture Notes

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Uploaded on
June 21, 2023
Number of pages
1
Written in
2022/2023
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Class notes
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Week 11

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THE ROLE OF THE ONCOLOGIST


Multidisciplinary Team Meeting
• Medical Oncologists
• Clinical Oncologists
• Pathologists
• Radiologists
• Surgeons
• Other tumour-type experts
• Gastroenterologists in GI cancers
• Respiratory physicians for lung cancers
• Clinical nurse specialists
• [MDT co-ordinators!]



Other Tests
• Immunohistochemistry for mismatch repair staining
• Loss of MSH6
• Small panel testing
• KRAS WT
• NRAS c.175G>A mutation
• BRAF WT
• MSH6 mutation




What Next?
• Completes 3 months of CAPOX
• Discharged to surgeons
• Follow up for 5 years
• CTs
• Colonoscopy
• Biomarkers
• CEA



2 Years Later
• Lost to follow-up from surveillance scans
• Presents with weight loss and jaundice
• Abdominal ultrasound scan
• 18cm liver tumour
• CT
• Bowel thickening
• Liver tumour

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