Exam 2023 with complete Solutions. 1. Neoadjuvant therapy does not increase survival when compared to ad-
juvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy: Main benefit of neoadjuvant chemotherapy (breast cancer patient)
2. A comprehensive geriatric assessment (CGA) is a multidisciplinary eval-
uation to assess life expectancy and risk of morbidity and mortality in the older patient. This assessment tool would evaluate and include the following areas: functional status, socioeconomic issues, psychosocial distress, co-
morbidities, cognitive function, nutritional status, polypharmacy, and a med-
ication review (NCCN Older Adult Oncology Guidelines, version 1.2015).: Due to Mrs. Turner's age and comorbidities, her oncologist performs a comprehensive geriatric assessment. You know that this assessment covers all but which of the following:
3. 65: The NCCN Older Adult Oncology Guidelines (version 1.2015) provides in-
formation on what is included in a comprehensive geriatric assessment. Currently, more than 60% of cancers in the United States occur in people age ______and older and as the oncology world ages, nearly half (46%) of cancer survivors are 70 years of age or older
4. Two of the agents (docetaxel and carboplatin) that Mrs. Turner will receive are categorized as irritants. Docetaxel can cause a significant reaction if it extravasates. It can lead to edema, erythema, occasional pain and blister for-
mation (ONS Chemo/Bio guidelines, 2014). That is the most likely reason that Mrs. Turner was given a port for her treatments. Some patients will receive their treatments through a peripheral IV without incident. Just because they are intravenous agents does not mean that a port is required and needing a port has nothing to do with her being older in age. Since none of these agents are vesicants, they likely could have been given safely via peripheral route but having a port placed is OK as well.: What is your best explanation for why Mrs. Turner was given a port to receive her chemotherapy?
5. Irrirtants: _____________can cause inflammation, pain, and burning but rarely cause tissue necrosis comparable to a vesicant (unless a large amount or a very high concentration of the irritant is extravasated).
6. Vesicants: _____________can cause blistering and significant pain and tissue damage and destruction, leading to tissue death.
7. Non-DNA-binding solutions remain in the local area of the extravasation, which improves the possibility of drug deactivation.